Normative MDCT cross-sectional data estimation of superior vena cava and innominate vein in growing children using age as a predictor

Karuna M. Das, Tariq S. Momenah, Rajvir Singh, Shanker Raja, Abdulrahman AlMoukirish, Mohammad AlZoum, Sven G. Larsson

Research output: Contribution to journalArticlepeer-review


This retrospective study aimed to determine the superior vena cava (SVC) and left innominate vein (INV) normative cross-sectional area in children noninvasively using age as a predictor and also to compare the correlation of the area measured with the diameter on multidetector computed tomography (MDCT). Analysis of the SVC-INV cross-sectional area was performed for 73 consecutive patients. The cross-sectional area of the SVC-INV was manually estimated. A regression analysis was performed for the cross-sectional area and age separately, and regression equations were compared. One-way analysis of variance (ANOVA) was performed to evaluate significant differences in the area means according to age groups. Regression analysis showed that age can be a predictor for the area of the SVC (50.6 mm2 + 1.01 × age), te INV (48.3 mm2 + 0.93 × age), and the left SVC-INV junction (47.2 mm 2 + 0.92 × age), with respective R2 values of 93, 88 and 94 %. The comparative evaluation of the cross-sectional area and the diameter measurement of SVC showed that the cross-sectional area was more closely associated with the increasing age of the cohort (R2 of 68 vs. 61 %) than the measured diameter. For a cohort of patients without congenital or acquired heart disease, MDCT can be used as a complementary test for a normative cross-sectional normogram area database of SVC-INV using age as a predictor.

Original languageEnglish
Pages (from-to)1030-1036
Number of pages7
JournalPediatric Cardiology
Issue number6
Publication statusPublished - Aug 2014
Externally publishedYes


  • Cavopulmonary connection
  • Complex congenital heart disease
  • Left innominate vein
  • Multidetector computed tomography
  • Normative MDCT cross-sectional area
  • Superior vena cava

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Cardiology and Cardiovascular Medicine


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