Novel finding of high density of activated mast cells in endometrial polyps

Moamar Al-Jefout; Kirsten Black; Lauren Schulke; Marina Berbic; Georgina Luscombe; Natsuko Tokushige; Frank Manconi; Robert Markham; Ian S. Fraser

doi:10.1016/j.fertnstert.2009.02.016

Novel finding of high density of activated mast cells in endometrial polyps

Moamar Al-Jefout, Kirsten Black, Lauren Schulke, Marina Berbic, Georgina Luscombe, Natsuko Tokushige, Frank Manconi, Robert Markham, Ian S. Fraser

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.

Original language	English
Pages (from-to)	1104-1106
Number of pages	3
Journal	Fertility and Sterility
Volume	92
Issue number	3
DOIs	https://doi.org/10.1016/j.fertnstert.2009.02.016
Publication status	Published - Sept 2009
Externally published	Yes

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynaecology

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10.1016/j.fertnstert.2009.02.016

Cite this

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abstract = "Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.",

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AU - Al-Jefout, Moamar

AU - Black, Kirsten

AU - Schulke, Lauren

AU - Berbic, Marina

AU - Luscombe, Georgina

AU - Tokushige, Natsuko

AU - Manconi, Frank

AU - Markham, Robert

AU - Fraser, Ian S.

PY - 2009/9

Y1 - 2009/9

N2 - Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.

AB - Endometrial polyps are benign lesions frequently identified in women with infertility or abnormal uterine bleeding in the reproductive and postmenopausal phases We report the striking observation that the numbers of activated mast cells expressing tryptase are increased more than sevenfold throughout the cycle in endometrial polyps (n = 20) compared with normal endometrium. This novel finding has important implications for growth, development, and symptoms associated with polyps in many different tissues.

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JO - Fertility and Sterility

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IS - 3

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Novel finding of high density of activated mast cells in endometrial polyps

Abstract

ASJC Scopus subject areas

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