Novel Pyran-Linked Phthalazinone-Pyrazole Hybrids: Synthesis, Cytotoxicity Evaluation, Molecular Modeling, and Descriptor Studies

Keyphrases

• Hybrid Synthesis 100%
• Pyrazole Hybrids 100%
• Phthalazinone 100%
• Solid Tumor Cell Lines 33%
• One-pot Three-component Reaction 33%
• Compound Descriptors 33%
• Lead-like 33%
• Biological Investigations 33%
• Active Methylene Compounds 33%
• Molecular Shape 33%
• Molecular Flexibility 33%
• 3D-QSAR Study 33%
• Flexibility Index 33%
• Shape Index 33%
• Drug-like 33%

Chemistry

• Pyran 100%
• 1H-Pyrazole 50%
• L-Proline 50%