Occurrence of hlyA and sheA genes in extraintestinal Escherichia coli strains

Monika Kerényi, Heather E. Allison, István Bátai, Ágnes Sonnevend, Levente Emödy, Nóra Plaveczky, Tibor Pál

Research output: Contribution to journalArticlepeer-review

43 Citations (Scopus)


The association of a hemolytic phenotype with the carriage of the α-hemolysin gene (hlyA) and/or the silent hemolysin gene (sheA or clyA) among 540 extraintestinal clinical isolates of Escherichia coli and 110 fecal isolates from healthy individuals was investigated. Though HlyA is an important virulence factor in extraintestinal E. coli infection, the role of SheA is not completely clarified. Two hemolytic sheA+ E. coli strains that lacked hlyA and possessed no other hemolysin genes were identified. No hlyA + sheA+ strains were identified, suggesting that there is possible incompatibility between hlyA and sheA in the chromosome of E. coli.

Original languageEnglish
Pages (from-to)2965-2968
Number of pages4
JournalJournal of Clinical Microbiology
Issue number6
Publication statusPublished - Jun 2005
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)


Dive into the research topics of 'Occurrence of hlyA and sheA genes in extraintestinal Escherichia coli strains'. Together they form a unique fingerprint.

Cite this