TY - GEN
T1 - On-chip electroporation
T2 - 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
AU - Ghafar-Zadeh, Ebrahim
AU - Gholamzadeh, Bahareh
AU - Awwad, Falah
AU - Sawan, Mohamad
PY - 2012
Y1 - 2012
N2 - In this paper, we describe an on-chip electroporation (EP) method for high precision nano-injection of bio-molecules into single cells. EP is an electrical stimulation method to create nano-pores on the cell plasma membrane. Herein, we first put forward the computational models of the cultured cells microelectrodes. We thereafter discuss practical considerations by demonstrating the preliminary experimental results. The mouse fibroblast cells are cultured above electrodes while experiencing a low frequency (10 Hz) electrical field (EF) in the presence of propidium iodide (PI).
AB - In this paper, we describe an on-chip electroporation (EP) method for high precision nano-injection of bio-molecules into single cells. EP is an electrical stimulation method to create nano-pores on the cell plasma membrane. Herein, we first put forward the computational models of the cultured cells microelectrodes. We thereafter discuss practical considerations by demonstrating the preliminary experimental results. The mouse fibroblast cells are cultured above electrodes while experiencing a low frequency (10 Hz) electrical field (EF) in the presence of propidium iodide (PI).
UR - http://www.scopus.com/inward/record.url?scp=84883037567&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84883037567&partnerID=8YFLogxK
U2 - 10.1109/EMBC.2012.6346492
DO - 10.1109/EMBC.2012.6346492
M3 - Conference contribution
C2 - 23366453
AN - SCOPUS:84883037567
SN - 9781424441198
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 2583
EP - 2586
BT - 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
Y2 - 28 August 2012 through 1 September 2012
ER -