One-pot synthesis of Cu-based metal-organic frameworks for environmental applications

Monika Nehra; Deepak Kedia; Neeraj Dilbaghi; Ashraf Aly Hassan; Sandeep Kumar

doi:10.1063/1.5113041

One-pot synthesis of Cu-based metal-organic frameworks for environmental applications

Monika Nehra, Deepak Kedia, Neeraj Dilbaghi, Ashraf Aly Hassan, Sandeep Kumar

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

Metal-organic frameworks (MOFs) are the coordination polymers of particular interest for targeted drug delivery in a controlled manner. MOFs have several interesting properties in terms of high porosity, large surface area, biodegradable and biocompatible nature for efficient encapsulation of active molecules. We have addressed here the challenge to load the active molecules of benzimidazole group during the synthesis of Cu-MOF. This one-pot approach is advantageous over existing approaches that require multistep post-functionalization for encapsulation of drug-molecules. The prepared MOFs are characterized using FT-IR, UV-Vis spectroscopy, XRD, and SEM analysis. The Cu-MOF are found incipient stable for delivery of active molecules along with high encapsulation efficiency (∼96%).

Original language	English
Title of host publication	DAE Solid State Physics Symposium 2018
Editors	Arup Biswas, Veerendra K. Sharma, S. M. Yusuf
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735418516
DOIs	https://doi.org/10.1063/1.5113041
Publication status	Published - Jul 11 2019
Externally published	Yes
Event	63rd DAE Solid State Physics Symposium 2018, DAE-SSPS 2018 - Hisar, Haryana, India Duration: Dec 18 2018 → Dec 22 2018

Publication series

Name	AIP Conference Proceedings
Volume	2115
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	63rd DAE Solid State Physics Symposium 2018, DAE-SSPS 2018
Country/Territory	India
City	Hisar, Haryana
Period	12/18/18 → 12/22/18

ASJC Scopus subject areas

General Physics and Astronomy

Access to Document

10.1063/1.5113041

Cite this

Nehra, M., Kedia, D., Dilbaghi, N., Hassan, A. A., & Kumar, S. (2019). One-pot synthesis of Cu-based metal-organic frameworks for environmental applications. In A. Biswas, V. K. Sharma, & S. M. Yusuf (Eds.), DAE Solid State Physics Symposium 2018 Article 030202 (AIP Conference Proceedings; Vol. 2115). American Institute of Physics Inc.. https://doi.org/10.1063/1.5113041

One-pot synthesis of Cu-based metal-organic frameworks for environmental applications. / Nehra, Monika; Kedia, Deepak; Dilbaghi, Neeraj et al.
DAE Solid State Physics Symposium 2018. ed. / Arup Biswas; Veerendra K. Sharma; S. M. Yusuf. American Institute of Physics Inc., 2019. 030202 (AIP Conference Proceedings; Vol. 2115).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Nehra, M, Kedia, D, Dilbaghi, N, Hassan, AA & Kumar, S 2019, One-pot synthesis of Cu-based metal-organic frameworks for environmental applications. in A Biswas, VK Sharma & SM Yusuf (eds), DAE Solid State Physics Symposium 2018., 030202, AIP Conference Proceedings, vol. 2115, American Institute of Physics Inc., 63rd DAE Solid State Physics Symposium 2018, DAE-SSPS 2018, Hisar, Haryana, India, 12/18/18. https://doi.org/10.1063/1.5113041

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abstract = "Metal-organic frameworks (MOFs) are the coordination polymers of particular interest for targeted drug delivery in a controlled manner. MOFs have several interesting properties in terms of high porosity, large surface area, biodegradable and biocompatible nature for efficient encapsulation of active molecules. We have addressed here the challenge to load the active molecules of benzimidazole group during the synthesis of Cu-MOF. This one-pot approach is advantageous over existing approaches that require multistep post-functionalization for encapsulation of drug-molecules. The prepared MOFs are characterized using FT-IR, UV-Vis spectroscopy, XRD, and SEM analysis. The Cu-MOF are found incipient stable for delivery of active molecules along with high encapsulation efficiency (∼96%).",

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AB - Metal-organic frameworks (MOFs) are the coordination polymers of particular interest for targeted drug delivery in a controlled manner. MOFs have several interesting properties in terms of high porosity, large surface area, biodegradable and biocompatible nature for efficient encapsulation of active molecules. We have addressed here the challenge to load the active molecules of benzimidazole group during the synthesis of Cu-MOF. This one-pot approach is advantageous over existing approaches that require multistep post-functionalization for encapsulation of drug-molecules. The prepared MOFs are characterized using FT-IR, UV-Vis spectroscopy, XRD, and SEM analysis. The Cu-MOF are found incipient stable for delivery of active molecules along with high encapsulation efficiency (∼96%).

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One-pot synthesis of Cu-based metal-organic frameworks for environmental applications

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