TY - GEN
T1 - One-pot synthesis of Cu-based metal-organic frameworks for environmental applications
AU - Nehra, Monika
AU - Kedia, Deepak
AU - Dilbaghi, Neeraj
AU - Hassan, Ashraf Aly
AU - Kumar, Sandeep
N1 - Funding Information:
Monika Nehra thanks the UGC, India for providing financial assistance in the form of JRF (award No. 3608 dated 29-02-2016).Sandeep Kumar thanks DST, Govt of India, University of Nebraska (UNL) Lincoln, the Daugherty Water for Food Institute (DWFI), and Indo-US Science and Technology Forum (IUSSTF) for financial support through Water Advanced Research and Innovation (WARI) research grant vide letter No. IUSSTF/WARI/2018/F-029-2018 dated 03-01-2018.
Publisher Copyright:
© 2019 Author(s).
PY - 2019/7/11
Y1 - 2019/7/11
N2 - Metal-organic frameworks (MOFs) are the coordination polymers of particular interest for targeted drug delivery in a controlled manner. MOFs have several interesting properties in terms of high porosity, large surface area, biodegradable and biocompatible nature for efficient encapsulation of active molecules. We have addressed here the challenge to load the active molecules of benzimidazole group during the synthesis of Cu-MOF. This one-pot approach is advantageous over existing approaches that require multistep post-functionalization for encapsulation of drug-molecules. The prepared MOFs are characterized using FT-IR, UV-Vis spectroscopy, XRD, and SEM analysis. The Cu-MOF are found incipient stable for delivery of active molecules along with high encapsulation efficiency (∼96%).
AB - Metal-organic frameworks (MOFs) are the coordination polymers of particular interest for targeted drug delivery in a controlled manner. MOFs have several interesting properties in terms of high porosity, large surface area, biodegradable and biocompatible nature for efficient encapsulation of active molecules. We have addressed here the challenge to load the active molecules of benzimidazole group during the synthesis of Cu-MOF. This one-pot approach is advantageous over existing approaches that require multistep post-functionalization for encapsulation of drug-molecules. The prepared MOFs are characterized using FT-IR, UV-Vis spectroscopy, XRD, and SEM analysis. The Cu-MOF are found incipient stable for delivery of active molecules along with high encapsulation efficiency (∼96%).
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U2 - 10.1063/1.5113041
DO - 10.1063/1.5113041
M3 - Conference contribution
AN - SCOPUS:85069774914
T3 - AIP Conference Proceedings
BT - DAE Solid State Physics Symposium 2018
A2 - Biswas, Arup
A2 - Sharma, Veerendra K.
A2 - Yusuf, S. M.
PB - American Institute of Physics Inc.
T2 - 63rd DAE Solid State Physics Symposium 2018, DAE-SSPS 2018
Y2 - 18 December 2018 through 22 December 2018
ER -