TY - GEN
T1 - Optimized local protein structure with support vector machine to predict protein secondary structure
AU - Chin, Yin Fai
AU - Hassan, Rohayanti
AU - Mohamad, Mohd Saberi
PY - 2012
Y1 - 2012
N2 - Protein includes many substances, such as enzymes, hormones and antibodies that are necessary for the organisms. Living cells are controlled by proteins and genes that interact through complex molecular pathways to achieve a specific function. These proteins have different shapes and structures which distinct them from each other. By having unique structures, only proteins able to carried out their function efficiently. Therefore, determination of protein structure is fundamental for the understanding of the cell's functions. The function of a protein is also largely determined by its structure. The importance of understanding protein structure has fueled the development of protein structure databases and prediction tools. Computational methods which were able to predict protein structure for the determination of protein function efficiently and accurately are in high demand. In this study, local protein structure with Support Vector Machine is proposed to predict protein secondary structure.
AB - Protein includes many substances, such as enzymes, hormones and antibodies that are necessary for the organisms. Living cells are controlled by proteins and genes that interact through complex molecular pathways to achieve a specific function. These proteins have different shapes and structures which distinct them from each other. By having unique structures, only proteins able to carried out their function efficiently. Therefore, determination of protein structure is fundamental for the understanding of the cell's functions. The function of a protein is also largely determined by its structure. The importance of understanding protein structure has fueled the development of protein structure databases and prediction tools. Computational methods which were able to predict protein structure for the determination of protein function efficiently and accurately are in high demand. In this study, local protein structure with Support Vector Machine is proposed to predict protein secondary structure.
KW - Local Protein Structure
KW - Protein Secondary Structure Prediction
KW - Support Vector Machine
UR - http://www.scopus.com/inward/record.url?scp=84865592387&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865592387&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-32826-8_34
DO - 10.1007/978-3-642-32826-8_34
M3 - Conference contribution
AN - SCOPUS:84865592387
SN - 9783642328251
T3 - Communications in Computer and Information Science
SP - 333
EP - 342
BT - Knowledge Technology - Third Knowledge Technology Week, KTW 2011, Revised Selected Papers
T2 - 3rd Knowledge Technology Week, KTW 2011
Y2 - 18 July 2011 through 22 July 2011
ER -