Organotin(IV) Complexes as Promising Potential Drug Candidates in the Field of Cancer Chemotherapy: A Narrative Review

Abeer Erfan; Emad Yousif; Ahmed Alshanon; Dina Saadi Ahmed; Muna Bufaroosha; Gamal El-Hiti

doi:10.54133/ajms.v5i.146

Organotin(IV) Complexes as Promising Potential Drug Candidates in the Field of Cancer Chemotherapy: A Narrative Review

Abeer Erfan, Emad Yousif, Ahmed Alshanon, Dina Saadi Ahmed, Muna Bufaroosha, Gamal El-Hiti

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

Abstract

Organotin(IV) complexes have a wide range of different applications. They are highly involved in pharmaceutical applications and have shown anticancer activity against various cancer cell lines. They act as antioxidants and can scavenge free radical species. The biological activity of organotin complexes depends on the organic moiety, type of substituents, number, type, and content of heteroatoms, and their geometry. The current review aimed to discuss using organotin complexes against different cancer cells.

Original language	English
Pages (from-to)	50-56
Number of pages	7
Journal	Al-Rafidain Journal of Medical Sciences
Volume	5
DOIs	https://doi.org/10.54133/ajms.v5i.146
Publication status	Published - 2023

Keywords

Anticancer activity
Antioxidants
Cephalexin
Medicinal and pharmaceutical applications
Organotin(IV) complexes

ASJC Scopus subject areas

Medicine(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.54133/ajms.v5i.146

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title = "Organotin(IV) Complexes as Promising Potential Drug Candidates in the Field of Cancer Chemotherapy: A Narrative Review",

abstract = "Organotin(IV) complexes have a wide range of different applications. They are highly involved in pharmaceutical applications and have shown anticancer activity against various cancer cell lines. They act as antioxidants and can scavenge free radical species. The biological activity of organotin complexes depends on the organic moiety, type of substituents, number, type, and content of heteroatoms, and their geometry. The current review aimed to discuss using organotin complexes against different cancer cells.",

keywords = "Anticancer activity, Antioxidants, Cephalexin, Medicinal and pharmaceutical applications, Organotin(IV) complexes",

author = "Abeer Erfan and Emad Yousif and Ahmed Alshanon and Ahmed, {Dina Saadi} and Muna Bufaroosha and Gamal El-Hiti",

note = "Publisher Copyright: {\textcopyright} 2023 The Author(s). Published by Al-Rafidain University College.",

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doi = "10.54133/ajms.v5i.146",

language = "English",

volume = "5",

pages = "50--56",

journal = "Al-Rafidain Journal of Medical Sciences",

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T1 - Organotin(IV) Complexes as Promising Potential Drug Candidates in the Field of Cancer Chemotherapy

T2 - A Narrative Review

AU - Erfan, Abeer

AU - Yousif, Emad

AU - Alshanon, Ahmed

AU - Ahmed, Dina Saadi

AU - Bufaroosha, Muna

AU - El-Hiti, Gamal

PY - 2023

Y1 - 2023

N2 - Organotin(IV) complexes have a wide range of different applications. They are highly involved in pharmaceutical applications and have shown anticancer activity against various cancer cell lines. They act as antioxidants and can scavenge free radical species. The biological activity of organotin complexes depends on the organic moiety, type of substituents, number, type, and content of heteroatoms, and their geometry. The current review aimed to discuss using organotin complexes against different cancer cells.

AB - Organotin(IV) complexes have a wide range of different applications. They are highly involved in pharmaceutical applications and have shown anticancer activity against various cancer cell lines. They act as antioxidants and can scavenge free radical species. The biological activity of organotin complexes depends on the organic moiety, type of substituents, number, type, and content of heteroatoms, and their geometry. The current review aimed to discuss using organotin complexes against different cancer cells.

KW - Anticancer activity

KW - Antioxidants

KW - Cephalexin

KW - Medicinal and pharmaceutical applications

KW - Organotin(IV) complexes

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VL - 5

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JO - Al-Rafidain Journal of Medical Sciences

JF - Al-Rafidain Journal of Medical Sciences

ER -

Organotin(IV) Complexes as Promising Potential Drug Candidates in the Field of Cancer Chemotherapy: A Narrative Review

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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