TY - JOUR
T1 - Overweight and obesity in pregnancy do not adversely affect neonatal outcomes
T2 - New evidence
AU - Narchi, H.
AU - Skinner, A.
PY - 2010/10
Y1 - 2010/10
N2 - We studied neonatal outcomes of infants of obese mothers in a cohort of 6,125 deliveries, using logistic multivariate analysis to remove the role of potential confounding variables. Although, as in previous reports, the crude unadjusted prevalence of several adverse neonatal outcomes was higher in these infants, the multivariable analysis revealed that only two outcomes remained significantly associated with maternal overweight and obesity: neonatal macrosomia (adjusted odds ratios aOR 1.4, p<0.001) and meconium aspiration syndrome (aOR 1.6, p0.05), indicating that the unadjusted association with the other outcomes was caused by confounding factors. Nonetheless, as macrosomia is associated with increased health risks both to the mothers and their infants, and maternal obesity with considerable maternal morbidity during pregnancy, these results should not lead to complacency, but instead encourage better prevention of obesity in general and during pregnancy in particular.
AB - We studied neonatal outcomes of infants of obese mothers in a cohort of 6,125 deliveries, using logistic multivariate analysis to remove the role of potential confounding variables. Although, as in previous reports, the crude unadjusted prevalence of several adverse neonatal outcomes was higher in these infants, the multivariable analysis revealed that only two outcomes remained significantly associated with maternal overweight and obesity: neonatal macrosomia (adjusted odds ratios aOR 1.4, p<0.001) and meconium aspiration syndrome (aOR 1.6, p0.05), indicating that the unadjusted association with the other outcomes was caused by confounding factors. Nonetheless, as macrosomia is associated with increased health risks both to the mothers and their infants, and maternal obesity with considerable maternal morbidity during pregnancy, these results should not lead to complacency, but instead encourage better prevention of obesity in general and during pregnancy in particular.
KW - Morbidity
KW - Newborn
KW - Obesity
KW - Pregnancy
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=77957852908&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77957852908&partnerID=8YFLogxK
U2 - 10.3109/01443615.2010.509824
DO - 10.3109/01443615.2010.509824
M3 - Article
C2 - 20925609
AN - SCOPUS:77957852908
SN - 0144-3615
VL - 30
SP - 679
EP - 686
JO - Journal of Obstetrics and Gynaecology
JF - Journal of Obstetrics and Gynaecology
IS - 7
ER -