TY - GEN
T1 - Parameter estimation using Improved Differential Evolution (IDE) and bacterial foraging algorithm to model tyrosine production in Mus Musculus (Mouse)
AU - Yeoh, Jia Xing
AU - Chong, Chuii Khim
AU - Choon, Yee Wen
AU - Chai, Lian En
AU - Deris, Safaai
AU - Illias, Rosli Md
AU - Mohamad, Mohd Saberi
PY - 2013
Y1 - 2013
N2 - The hybrid of Differential Evolution algorithm with Kalman Filtering and Bacterial Foraging algorithm is a novel global optimization method that is implemented in this research to obtain the best kinetic parameter value. The proposed algorithm is then used to model tyrosine production in mus musculus (mouse) by using a dataset, JAK/STAT (Janus Kinase Signal Transducer and Activator of Transcription) signal transduction pathway. Global optimization is a method to identify the optimal kinetic parameter using ordinary differential equation. From the ordinary parameter of biomathematical field, there are many unknown parameters and commonly the parameters are in nonlinear form. Global optimization method includes differential evolution algorithm which will be used in this research. Kalman Filter and Bacterial Foraging algorithm help in handling noise data and faster convergences respectively in the conventional Differential Evolution. The results from this experiment show estimatedly optimal kinetic parameters values, shorter computation time, and better accuracy of simulated results compared with other estimation algorithms.
AB - The hybrid of Differential Evolution algorithm with Kalman Filtering and Bacterial Foraging algorithm is a novel global optimization method that is implemented in this research to obtain the best kinetic parameter value. The proposed algorithm is then used to model tyrosine production in mus musculus (mouse) by using a dataset, JAK/STAT (Janus Kinase Signal Transducer and Activator of Transcription) signal transduction pathway. Global optimization is a method to identify the optimal kinetic parameter using ordinary differential equation. From the ordinary parameter of biomathematical field, there are many unknown parameters and commonly the parameters are in nonlinear form. Global optimization method includes differential evolution algorithm which will be used in this research. Kalman Filter and Bacterial Foraging algorithm help in handling noise data and faster convergences respectively in the conventional Differential Evolution. The results from this experiment show estimatedly optimal kinetic parameters values, shorter computation time, and better accuracy of simulated results compared with other estimation algorithms.
KW - Bacterial foraging algorithm
KW - Differential evolution algorithm
KW - Kalman filtering algorithm
KW - Modeling
KW - Parameter estimation
UR - http://www.scopus.com/inward/record.url?scp=84892838018&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84892838018&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-40319-4_16
DO - 10.1007/978-3-642-40319-4_16
M3 - Conference contribution
AN - SCOPUS:84892838018
SN - 9783642403187
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 179
EP - 190
BT - Trends and Applications in Knowledge Discovery and Data Mining - PAKDD 2013 International Workshops
T2 - 17th Pacific-Asia Conference on Knowledge Discovery and Data Mining, PAKDD 2013
Y2 - 14 April 2013 through 17 April 2013
ER -