Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches

M. F. Misman; S. Deris; S. Z.M. Hashim; R. Jumali; M. S. Mohamad

doi:10.1109/ICIME.2009.103

Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches

M. F. Misman, S. Deris, S. Z.M. Hashim, R. Jumali, M. S. Mohamad

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

9 Citations (Scopus)

Abstract

In this reiew, we have discussed about approaches in pathway based microarray analysis. Commonly, there are two approaches in pathway based analysis, Enrichment Score and Supervised Machine Learning. These pathway based approaches usually aim to statistically define significant pathways that related to phenotypes of interest. Firstly we discussed an overview of pathway based microarray analysis and its general flow processes in scoring the pathways, the methods applied in both approaches, advantages and limitations based on current researches, and pathways database used in pathway analysis. This review aim to provide better understanding about pathway based microarray analysis and its approaches.

Original language	English
Title of host publication	Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009
Pages	496-500
Number of pages	5
DOIs	https://doi.org/10.1109/ICIME.2009.103
Publication status	Published - 2009
Externally published	Yes
Event	2009 International Conference on Information Management and Engineering, ICIME 2009 - Kuala Lumpur, Malaysia Duration: Apr 3 2009 → Apr 5 2009

Publication series

Name	Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009

Other

Other	2009 International Conference on Information Management and Engineering, ICIME 2009
Country/Territory	Malaysia
City	Kuala Lumpur
Period	4/3/09 → 4/5/09

Keywords

Machine learning
Microarray
Pathway analysis

ASJC Scopus subject areas

Computer Science Applications
Information Systems
Information Systems and Management

Access to Document

10.1109/ICIME.2009.103

Cite this

Misman, M. F., Deris, S., Hashim, S. Z. M., Jumali, R., & Mohamad, M. S. (2009). Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches. In Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009 (pp. 496-500). Article 5077084 (Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009). https://doi.org/10.1109/ICIME.2009.103

Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches. / Misman, M. F.; Deris, S.; Hashim, S. Z.M. et al.
Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009. 2009. p. 496-500 5077084 (Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Misman, MF, Deris, S, Hashim, SZM, Jumali, R & Mohamad, MS 2009, Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches. in Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009., 5077084, Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009, pp. 496-500, 2009 International Conference on Information Management and Engineering, ICIME 2009, Kuala Lumpur, Malaysia, 4/3/09. https://doi.org/10.1109/ICIME.2009.103

Misman MF, Deris S, Hashim SZM, Jumali R, Mohamad MS. Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches. In Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009. 2009. p. 496-500. 5077084. (Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009). doi: 10.1109/ICIME.2009.103

Misman, M. F. ; Deris, S. ; Hashim, S. Z.M. et al. / Pathway-based microarray analysis for defining statistical significant phenotype-related pathways : A review of common approaches. Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009. 2009. pp. 496-500 (Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009).

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abstract = "In this reiew, we have discussed about approaches in pathway based microarray analysis. Commonly, there are two approaches in pathway based analysis, Enrichment Score and Supervised Machine Learning. These pathway based approaches usually aim to statistically define significant pathways that related to phenotypes of interest. Firstly we discussed an overview of pathway based microarray analysis and its general flow processes in scoring the pathways, the methods applied in both approaches, advantages and limitations based on current researches, and pathways database used in pathway analysis. This review aim to provide better understanding about pathway based microarray analysis and its approaches.",

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Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: A review of common approaches

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