Peptide YY

T. E. Adrian

doi:10.1016/B978-0-12-809324-5.03307-1

Peptide YY

T. E. Adrian

Department of Physiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Peptide YY (PYY) is a hormonal peptide produced by endocrine cells in the intestinal mucosa. This chapter reviews the discovery of the peptide, its structure and that if its gene, its distribution, release mechanism, receptors, biological and physiological effects, its role in pathophysiology and finally its therapeutic potential. In 2002, PYY was shown to have marked inhibitory effects on food intake. Since then there has been an explosion of research into its role in obesity and metabolic disease as well as its potential for therapy in this area.

Original language	English
Title of host publication	The Curated Reference Collection in Neuroscience and Biobehavioral Psychology
Publisher	Elsevier Science Ltd.
Pages	161-170
Number of pages	10
ISBN (Electronic)	9780128093245
DOIs	https://doi.org/10.1016/B978-0-12-809324-5.03307-1
Publication status	Published - Jan 1 2016

Keywords

Anti-secretory
Bariatric surgery
Enteroendocrine L-cell
Food intake
Gastrointestinal hormone
Glucose homeostasis
Hypothalamus
Peptide YY
Peptide tyrosine tyrosine
Satiety
Weight loss
Y receptors

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-809324-5.03307-1

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abstract = "Peptide YY (PYY) is a hormonal peptide produced by endocrine cells in the intestinal mucosa. This chapter reviews the discovery of the peptide, its structure and that if its gene, its distribution, release mechanism, receptors, biological and physiological effects, its role in pathophysiology and finally its therapeutic potential. In 2002, PYY was shown to have marked inhibitory effects on food intake. Since then there has been an explosion of research into its role in obesity and metabolic disease as well as its potential for therapy in this area.",

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KW - Anti-secretory

KW - Bariatric surgery

KW - Enteroendocrine L-cell

KW - Food intake

KW - Gastrointestinal hormone

KW - Glucose homeostasis

KW - Hypothalamus

KW - Peptide YY

KW - Peptide tyrosine tyrosine

KW - Satiety

KW - Weight loss

KW - Y receptors

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BT - The Curated Reference Collection in Neuroscience and Biobehavioral Psychology

PB - Elsevier Science Ltd.

ER -

Peptide YY

Abstract

Keywords

ASJC Scopus subject areas

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