The initial interaction of Shigella flexneri with HeLa cells was studied at 4°C, a temperature that inhibits parasite-directed endocytosis. It was found that invasive strains were 10-fold more adherent to HeLa cells than were isogenic, noninvasive strains which had lost a 140-megadalton plasmid. Adherent strains were also more hydrophobic than were nonadherent strains.
|Number of pages||3|
|Journal||Infection and Immunity|
|Publication status||Published - Jan 1 1989|
ASJC Scopus subject areas
- Infectious Diseases