Plasmid-associated adherence of Shigella flexneri in a HeLa cell model

T. Pal, T. L. Hale

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


The initial interaction of Shigella flexneri with HeLa cells was studied at 4°C, a temperature that inhibits parasite-directed endocytosis. It was found that invasive strains were 10-fold more adherent to HeLa cells than were isogenic, noninvasive strains which had lost a 140-megadalton plasmid. Adherent strains were also more hydrophobic than were nonadherent strains.

Original languageEnglish
Pages (from-to)2580-2582
Number of pages3
JournalInfection and Immunity
Issue number8
Publication statusPublished - 1989
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases


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