TY - JOUR
T1 - Polymeric nanobiocomposites for biomedical applications
AU - Mozumder, Mohammad Sayem
AU - Mairpady, Anusha
AU - Mourad, Abdel Hamid I.
N1 - Publisher Copyright:
© 2016 Wiley Periodicals, Inc.
PY - 2017/7
Y1 - 2017/7
N2 - Polymeric nanobiocomposites have recently become one of the most essential sought after materials for biomedical applications ranging from implants to the creation of gels. Their unique mechanical and biological properties provide them the ability to pass through the highly guarded defense mechanism without undergoing noticeable degradation and initiation of immune responses, which in turn makes them advantageous over the other alternatives. Aligned with the advances in tissue engineering, it is also possible to design three-dimensional extracellular matrix using these polymeric nanobiocomposites that could closely mimic the human tissues. In fact, unique polymer chemistry coupled with nanoparticles could create unique microenvironment that promotes cell growth and differentiation. In addition, the nanobiocomposites can also be devised to carry drugs efficiently to the target site without exhibiting any cytotoxicity as well as to eradicate surgical infections. In this article, an effort has been made to thoroughly review a number of different types/classes of polymeric nanocomposites currently used in biomedical fields.
AB - Polymeric nanobiocomposites have recently become one of the most essential sought after materials for biomedical applications ranging from implants to the creation of gels. Their unique mechanical and biological properties provide them the ability to pass through the highly guarded defense mechanism without undergoing noticeable degradation and initiation of immune responses, which in turn makes them advantageous over the other alternatives. Aligned with the advances in tissue engineering, it is also possible to design three-dimensional extracellular matrix using these polymeric nanobiocomposites that could closely mimic the human tissues. In fact, unique polymer chemistry coupled with nanoparticles could create unique microenvironment that promotes cell growth and differentiation. In addition, the nanobiocomposites can also be devised to carry drugs efficiently to the target site without exhibiting any cytotoxicity as well as to eradicate surgical infections. In this article, an effort has been made to thoroughly review a number of different types/classes of polymeric nanocomposites currently used in biomedical fields.
KW - biological properties
KW - mechanical properties
KW - nanobiocomposites
KW - polymer
KW - scaffolds
KW - tissue engineering
UR - http://www.scopus.com/inward/record.url?scp=84959449737&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84959449737&partnerID=8YFLogxK
U2 - 10.1002/jbm.b.33633
DO - 10.1002/jbm.b.33633
M3 - Review article
C2 - 26910862
AN - SCOPUS:84959449737
SN - 1552-4973
VL - 105
SP - 1241
EP - 1259
JO - Journal of Biomedical Materials Research - Part B Applied Biomaterials
JF - Journal of Biomedical Materials Research - Part B Applied Biomaterials
IS - 5
ER -