Polyphosphazene-hydroxyapatite composites as scaffolds for bone tissue engineering

S. Lakshmi, Y. E. Greish, J. W. Freeman, J. D. Bender, P. W. Brown, H. R. Allcock, C. T. Laurencin

Research output: Chapter in Book/Report/Conference proceedingConference contribution


A method that enables the synthesis of bone like apatites at physiological conditions through a cement-like reaction from hydroxyapatite precursors (HAp) such as tetracalcium phosphate (TetCP) and dicalcium phosphate (DCPA), was presented. The feasibility of developing HAp-biodegradable polyphosphazenes composites as suitable materials for bone tissue engineering were demonstrated. X-ray diffraction analysis of the HAp and composites were performed using an automated diffractometer, and the changes in mechanical properties were recorded. It was found that the incorporation of polyphosphazenes significantly improves cell adhesion and proliferation on the composites.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Number of pages1
Publication statusPublished - 2004
Externally publishedYes
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Publication series

NameTransactions - 7th World Biomaterials Congress


OtherTransactions - 7th World Biomaterials Congress

ASJC Scopus subject areas

  • General Engineering


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