TY - JOUR
T1 - Post mortem aqueous humor analysis in sheep as index of ante mortem serum biochemistry profile
AU - Athanasiou, L. V.
AU - Christodoulopoulos, G.
AU - Polizopoulou, Z. S.
AU - Kalaitzakis, E.
AU - Papadakis, S. M.
AU - Karatzia, M. A.
AU - Katsogiannou, E. G.
AU - Katsoulos, P. D.
N1 - Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2018/2/1
Y1 - 2018/2/1
N2 - We investigated the usefulness of the concentration of total proteins, albumin, creatinine, calcium (Ca), magnesium (Mg) and the activities of aspartate aminotransferase (AST) and gamma-glutamyltransferase (GGT) in aqueous humor in estimating the ante mortem levels of the same biochemical analytes in sheep blood. A blood sample was taken ante mortem and aqueous humor was collected 12 h post mortem from 63 sheep. Linear Regression Analysis was run to determine the equations predicting the serum value of each parameter based on the value determined in aqueous humor for those parameters that were significantly correlated. A strong relationship was found for Mg and creatinine concentration as well as for AST and GGT activities in aqueous humor and serum. Aqueous humor analysis of creatinine, Mg, AST and GGT levels can be used for the estimation of the corresponding concentration in blood, while, total proteins, albumin and Ca levels are of limited value.
AB - We investigated the usefulness of the concentration of total proteins, albumin, creatinine, calcium (Ca), magnesium (Mg) and the activities of aspartate aminotransferase (AST) and gamma-glutamyltransferase (GGT) in aqueous humor in estimating the ante mortem levels of the same biochemical analytes in sheep blood. A blood sample was taken ante mortem and aqueous humor was collected 12 h post mortem from 63 sheep. Linear Regression Analysis was run to determine the equations predicting the serum value of each parameter based on the value determined in aqueous humor for those parameters that were significantly correlated. A strong relationship was found for Mg and creatinine concentration as well as for AST and GGT activities in aqueous humor and serum. Aqueous humor analysis of creatinine, Mg, AST and GGT levels can be used for the estimation of the corresponding concentration in blood, while, total proteins, albumin and Ca levels are of limited value.
KW - Aqueous humor
KW - Biochemical analysis
KW - Blood
KW - Sheep
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U2 - 10.1016/j.smallrumres.2018.01.003
DO - 10.1016/j.smallrumres.2018.01.003
M3 - Article
AN - SCOPUS:85042922560
SN - 0921-4488
VL - 159
SP - 52
EP - 55
JO - Small Ruminant Research
JF - Small Ruminant Research
ER -