Potato steroidal glycoalkaloids: properties, biosynthesis, regulation and genetic manipulation

Yongming Liu; Xiaowei Liu; Yingge Li; Yanfei Pei; Abdul Jaleel; Maozhi Ren

doi:10.1186/s43897-024-00118-y

Potato steroidal glycoalkaloids: properties, biosynthesis, regulation and genetic manipulation

Yongming Liu
, Xiaowei Liu
, Yingge Li
, Yanfei Pei
, Abdul Jaleel
, Maozhi Ren

Department of Integrative Agriculture

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

Abstract

Steroidal glycoalkaloids (SGAs), predominantly comprising α-solanine (C₄₅H₇₃NO₁₅) and α-chaconine (C₄₅H₇₃NO₁₄), function as natural phytotoxins within potatoes. In addition to their other roles, these SGAs are crucial for enabling potato plants to withstand biotic stresses. However, they also exhibit toxicity towards humans and animals. Consequently, the content and distribution of SGAs are crucial traits for the genetic improvement of potatoes. This review focuses on advancing research related to the biochemical properties, biosynthesis, regulatory mechanisms, and genetic improvement of potato SGAs. Furthermore, we provide perspectives on future research directions to further enhance our understanding of SGA biosynthesis and regulation, ultimately facilitating the targeted development of superior potato varieties.

Original language	English
Article number	43
Journal	Molecular Horticulture
Volume	4
Issue number	1
DOIs	https://doi.org/10.1186/s43897-024-00118-y
Publication status	Published - Dec 2024

Keywords

Antinutritional factors
Biosynthesis
Potato
Quality improvement
Regulation network
Steroidal glycoalkaloids
Toxicity

ASJC Scopus subject areas

Horticulture
Plant Science
Molecular Biology
Agronomy and Crop Science

Access to Document

10.1186/s43897-024-00118-y

Cite this

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title = "Potato steroidal glycoalkaloids: properties, biosynthesis, regulation and genetic manipulation",

abstract = "Steroidal glycoalkaloids (SGAs), predominantly comprising α-solanine (C45H73NO15) and α-chaconine (C45H73NO14), function as natural phytotoxins within potatoes. In addition to their other roles, these SGAs are crucial for enabling potato plants to withstand biotic stresses. However, they also exhibit toxicity towards humans and animals. Consequently, the content and distribution of SGAs are crucial traits for the genetic improvement of potatoes. This review focuses on advancing research related to the biochemical properties, biosynthesis, regulatory mechanisms, and genetic improvement of potato SGAs. Furthermore, we provide perspectives on future research directions to further enhance our understanding of SGA biosynthesis and regulation, ultimately facilitating the targeted development of superior potato varieties.",

keywords = "Antinutritional factors, Biosynthesis, Potato, Quality improvement, Regulation network, Steroidal glycoalkaloids, Toxicity",

author = "Yongming Liu and Xiaowei Liu and Yingge Li and Yanfei Pei and Abdul Jaleel and Maozhi Ren",

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doi = "10.1186/s43897-024-00118-y",

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TY - JOUR

T1 - Potato steroidal glycoalkaloids

T2 - properties, biosynthesis, regulation and genetic manipulation

AU - Liu, Yongming

AU - Liu, Xiaowei

AU - Li, Yingge

AU - Pei, Yanfei

AU - Jaleel, Abdul

AU - Ren, Maozhi

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/12

Y1 - 2024/12

N2 - Steroidal glycoalkaloids (SGAs), predominantly comprising α-solanine (C45H73NO15) and α-chaconine (C45H73NO14), function as natural phytotoxins within potatoes. In addition to their other roles, these SGAs are crucial for enabling potato plants to withstand biotic stresses. However, they also exhibit toxicity towards humans and animals. Consequently, the content and distribution of SGAs are crucial traits for the genetic improvement of potatoes. This review focuses on advancing research related to the biochemical properties, biosynthesis, regulatory mechanisms, and genetic improvement of potato SGAs. Furthermore, we provide perspectives on future research directions to further enhance our understanding of SGA biosynthesis and regulation, ultimately facilitating the targeted development of superior potato varieties.

AB - Steroidal glycoalkaloids (SGAs), predominantly comprising α-solanine (C45H73NO15) and α-chaconine (C45H73NO14), function as natural phytotoxins within potatoes. In addition to their other roles, these SGAs are crucial for enabling potato plants to withstand biotic stresses. However, they also exhibit toxicity towards humans and animals. Consequently, the content and distribution of SGAs are crucial traits for the genetic improvement of potatoes. This review focuses on advancing research related to the biochemical properties, biosynthesis, regulatory mechanisms, and genetic improvement of potato SGAs. Furthermore, we provide perspectives on future research directions to further enhance our understanding of SGA biosynthesis and regulation, ultimately facilitating the targeted development of superior potato varieties.

KW - Antinutritional factors

KW - Biosynthesis

KW - Potato

KW - Quality improvement

KW - Regulation network

KW - Steroidal glycoalkaloids

KW - Toxicity

UR - https://www.scopus.com/pages/publications/85211922199

UR - https://www.scopus.com/pages/publications/85211922199#tab=citedBy

U2 - 10.1186/s43897-024-00118-y

DO - 10.1186/s43897-024-00118-y

M3 - Review article

AN - SCOPUS:85211922199

SN - 2730-9401

VL - 4

JO - Molecular Horticulture

JF - Molecular Horticulture

IS - 1

M1 - 43

ER -

Potato steroidal glycoalkaloids: properties, biosynthesis, regulation and genetic manipulation

Abstract

Keywords

ASJC Scopus subject areas

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