Prediction of inter-domain linker regions in protein sequences: A survey

Maad Shatnawi, Nazar Zaki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Protein chains are typically large and consist of multiple domains which are difficult and computationally expensive to characterize by experimental methods. Therefore, accurate and reliable prediction of protein domain boundaries is often the primary step in both experimental and computational protein research. This paper surveys several prediction techniques of inter-domain linker segments within protein sequences and summarizes the key technical challenges and unresolved issues. The paper investigates most of the relevant existing approaches carried out towards this perspective and provides a comparison of these approaches. Future research directions in this area are also discussed.

Original languageEnglish
Title of host publication2013 9th International Conference on Innovations in Information Technology, IIT 2013
Pages237-242
Number of pages6
DOIs
Publication statusPublished - 2013
Event2013 9th International Conference on Innovations in Information Technology, IIT 2013 - Abu Dhabi, Al-Ain, United Arab Emirates
Duration: Mar 17 2013Mar 19 2013

Publication series

Name2013 9th International Conference on Innovations in Information Technology, IIT 2013

Other

Other2013 9th International Conference on Innovations in Information Technology, IIT 2013
Country/TerritoryUnited Arab Emirates
CityAbu Dhabi, Al-Ain
Period3/17/133/19/13

Keywords

  • Domain boundary prediction
  • domain linkers
  • inter-domain linker regions
  • protein sequences

ASJC Scopus subject areas

  • Management of Technology and Innovation
  • Information Systems

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