TY - JOUR
T1 - Preliminary results of a single-arm pilot study to assess the safety and efficacy of visnadine, prenylflavonoids and bovine colostrum in postmenopausal sexually active women affected by vulvovaginal atrophy
AU - Laganà, Antonio Simone
AU - Vitale, Salvatore Giovanni
AU - Stojanovska, Lily
AU - Lambrinoudaki, Irene
AU - Apostolopoulos, Vasso
AU - Chiofalo, Benito
AU - Rizzo, Laura
AU - Basile, Francesca
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2018/3
Y1 - 2018/3
N2 - This single-arm pilot study enrolled 47 post-menopausal women affected by vulvovaginal atrophy (VVA). The Vaginal Health Index Score (VHIS) was evaluated for all women and all completed the Female Sexual Function Index (FSFI) questionnaire at baseline (T0) and after 15 days of vaginal cream treatment with one application per day (T1). Following treatment there was a significant improvement in all VHIS parameters and total score (p < 0.0001). Similarly, there was a significant improvement on four FSFI domains (lubrication, orgasm, satisfaction and pain) and total score (p = 0.001). None of the patients reported any local or systemic side-effects during treatment.
AB - This single-arm pilot study enrolled 47 post-menopausal women affected by vulvovaginal atrophy (VVA). The Vaginal Health Index Score (VHIS) was evaluated for all women and all completed the Female Sexual Function Index (FSFI) questionnaire at baseline (T0) and after 15 days of vaginal cream treatment with one application per day (T1). Following treatment there was a significant improvement in all VHIS parameters and total score (p < 0.0001). Similarly, there was a significant improvement on four FSFI domains (lubrication, orgasm, satisfaction and pain) and total score (p = 0.001). None of the patients reported any local or systemic side-effects during treatment.
KW - Bovine colostrum
KW - Menopause
KW - Prenylflavonoids
KW - Sexual wellbeing
KW - Visnadine
KW - Vulvovaginal atrophy
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UR - http://www.scopus.com/inward/citedby.url?scp=85039436733&partnerID=8YFLogxK
U2 - 10.1016/j.maturitas.2017.12.015
DO - 10.1016/j.maturitas.2017.12.015
M3 - Article
C2 - 29452786
AN - SCOPUS:85039436733
SN - 0378-5122
VL - 109
SP - 78
EP - 80
JO - Maturitas
JF - Maturitas
ER -