Presence of alkylresorcinols, potential whole grain biomarkers, in human adipose tissue

Erika Jansson, Rikard Landberg, Afaf Kamal-Eldin, Alicja Wolk, Bengt Vessby, Per Aman

Research output: Contribution to journalArticlepeer-review

33 Citations (Scopus)


Alkylresorcinols (AR) in plasma samples have been suggested to be short- to medium-term biomarkers of whole grain wheat and rye intake. In the present study, we investigated whether AR are present in human adipose tissues, and if content correlated with long-term whole grain bread intake. Furthermore, we investigated if the relative AR homologue composition reflected what has been found previously in the habitual diet of Swedes. Biopsy samples (10-25mg) from free-living Swedish women (n 20) were analysed by GC-MS. The mean total AR concentration in the samples was 054 (sd 035)g/g, ranging from below limit of quantification (<008g/g) to 150g/g. Whole grain bread intake was significantly correlated with plasma total AR content (r 048, P<005), and the C17:0/C21:0 ratio was 035 (sd 024), which is similar to what is found in plasma among free-living subjects consuming a mixed whole grain wheat and rye diet. These results suggest that AR in the adipose tissue should be evaluated as a long-term biomarker of whole grain wheat and rye intake.

Original languageEnglish
Pages (from-to)633-636
Number of pages4
JournalBritish Journal of Nutrition
Issue number5
Publication statusPublished - Sept 14 2010
Externally publishedYes


  • Adipose tissue
  • Alkylresorcinols
  • Biomarker
  • Long term
  • Whole grain

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


Dive into the research topics of 'Presence of alkylresorcinols, potential whole grain biomarkers, in human adipose tissue'. Together they form a unique fingerprint.

Cite this