Prevalence and incidence of hepatitis A among male homosexuals

R. A. Coutinho, P. Albrecht-van Lent, N. Lelie, N. Nagelkerke, H. Kuipers, T. Rijsdijk

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32 Citations (Scopus)


In a study of 689 male homosexuals 290 (42%) were found to have antibodies to hepatitis A virus. The 399 men who did not have antibodies were followed up for up to 690 days, and 35 cases of hepatitis A were detected. The attack rate at the end of the study was 14%. The incidence climbed steadily, indicating that the cases of hepatitis A did not occur in clusters. Statistical analysis showed that the prevalence of antibodies to hepatitis A virus was significantly correlated with the duration of homosexual activity (p<0.006), and this was independent of age. The incidence of hepatitis A was found to be correlated with the number of different sexual partners in the preceding six months. It is concluded that hepatitis A is a sexually transmitted disease among homosexual men in countries with a low rate of exposure to hepatitis A during childhood.

Original languageEnglish
Pages (from-to)1743-1745
Number of pages3
JournalBritish Medical Journal
Issue number6407
Publication statusPublished - Dec 1 1983

ASJC Scopus subject areas

  • General Medicine


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