Prognostication of Incidence and Severity of Ischemic Stroke in Hot Dry Climate From Environmental and Non-Environmental Predictors

Yauhen Statsenko, Tetiana Habuza, Ekaterina Fursa, Anna Ponomareva, Taleb M. Almansoori, Fatmah Al Zahmi, Klaus Neidl Van Gorkom, Vasyl Laver, Tatsiana Talako, Miklos Szolics, Alireza Dehdashtian, Jamal Al Koteesh, Milos Ljubisavljevic

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background: Recently, rapid fluctuations of ambient temperature were found to be associated with hospital admission for cardiovascular diseases in general and the ischemic stroke in particular. Objective: to test if climatic factors predict the incidence of stroke reliably and to study the predictive potential of risk factors for a stroke. Materials and methods: In a retrospective design, we studied 566 patients admitted to the stroke unit in 2016-2019. A distributed lag nonlinear model was used to explore immediate and delayed effects of weather and clinicodemographic risk factors on the stroke incidence. Supervised machine learning was used to build models predictive of the mRS score. We assessed model performance by calculating R2 , mean absolute error and root-mean-square error. Results and conclusions: We found a non-correlation between the weather parameters and statistics on stroke. The disparities in their trends lead us to investigate behind time effects of the environment with distributed lag models and a concordant impact of all the settings - with machine learning models. If categorized into two classes by severity and functional outcomes, the cases have few disparities in the weather parameters within a week before the stroke onset. In contrast to the groups classified by severity, the ones grouped by outcomes have a significant difference in age, nationality, the presence of background diseases and smoking status. We ranked environmental and individual risk factors by the information gain that they provide to the models. Inclusion of the weather parameters into the machine learning model predicting the mRS score provides a slight boost in performance.

Original languageEnglish
Pages (from-to)58268-58286
Number of pages19
JournalIEEE Access
Volume10
DOIs
Publication statusPublished - 2022

Keywords

  • Ethnicity
  • Ischemic stroke
  • Machine learning classification model
  • Middle east
  • Risk
  • Sex
  • Weather

ASJC Scopus subject areas

  • General Engineering
  • General Computer Science
  • General Materials Science

Fingerprint

Dive into the research topics of 'Prognostication of Incidence and Severity of Ischemic Stroke in Hot Dry Climate From Environmental and Non-Environmental Predictors'. Together they form a unique fingerprint.

Cite this