Radial flow tubular membrane bioreactor for enhanced enzymatic hydrolysis of lignocellulosic waste biomass

Saleha Al-Mardeai, Emad Elnajjar, Raed Hashaikeh, Boguslaw Kruczek, Bart Van der Bruggen, Sulaiman Al-Zuhair

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


A tubular membrane bioreactor was used for enhanced enzymatic hydrolysis of waste biomass, palm date seeds. The bioreactor successfully handled high solid loadings with effective simultaneous product removal. The effects of substrate concentrations, 14.3, 21.4, and 39.6 g/L, and water flowrates, 0.4, 0.8, and 1.2 mL/min, on the production of total reducing sugars were examined. At substrate concentration of 21.4 g/L, the total reducing sugars yield increased from 28.9 % to 42.7 % after 8 h as the water flowrate increased from 0.4 to 1.2 mL/min. Substrate inhibition was observed at the highest tested substrate concentration of 39.6 g/L. A dynamic model was developed to describe the designed bioreactor, accounting for the simultaneous product separation and the dynamic changes in substrate structure. The nonhydrolyzable substrate fraction parameter was found to significantly affect the model prediction. The novel membrane bioreactor and the developed model enable the industrial valorization of lignocellulosic biomass for bioethanol production.

Original languageEnglish
Article number127648
Publication statusPublished - Jun 1 2023


  • Enzymatic hydrolysis
  • Kinetic model
  • Membrane bioreactor
  • Product inhibition
  • Product separation

ASJC Scopus subject areas

  • General Chemical Engineering
  • Fuel Technology
  • Energy Engineering and Power Technology
  • Organic Chemistry


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