Raising concerns about the Sepsis-3 definitions

Massimo Sartelli; Yoram Kluger; Luca Ansaloni; Timothy C. Hardcastle; Jordi Rello; Richard R. Watkins; Matteo Bassetti; Eleni Giamarellou; Federico Coccolini; Fikri M. Abu-Zidan; Abdulrashid K. Adesunkanmi; Goran Augustin; Gian L. Baiocchi; Miklosh Bala; Oussema Baraket; Marcelo A. Beltran; Asri Che Jusoh; Zaza Demetrashvili; Belinda De Simone; Hamilton P. de Souza; Yunfeng Cui; R. Justin Davies; Sameer Dhingra; Jose J. Diaz; Salomone Di Saverio; Agron Dogjani; Mutasim M. Elmangory; Mushira A. Enani; Paula Ferrada; Gustavo P. Fraga; Sabrina Frattima; Wagih Ghnnam; Carlos A. Gomes; Souha S. Kanj; Aleksandar Karamarkovic; Jakub Kenig; Faryal Khamis; Vladimir Khokha; Kaoru Koike; Kenneth Y.Y. Kok; Arda Isik; Francesco M. Labricciosa; Rifat Latifi; Jae G. Lee; Andrey Litvin; Gustavo M. Machain; Ramiro Manzano-Nunez; Piotr Major; Sanjay Marwah; Michael McFarlane; Ziad A. Memish; Cristian Mesina; Ernest E. Moore; Frederick A. Moore; Noel Naidoo; Ionut Negoi; Richard Ofori-Asenso; Iyiade Olaoye; Carlos A. Ordoñez; Mouaqit Ouadii; Ciro Paolillo; Edoardo Picetti; Tadeja Pintar; Alfredo Ponce-de-Leon; Guntars Pupelis; Tarcisio Reis; Boris Sakakushev; Hossein Samadi Kafil; Norio Sato; Jay N. Shah; Boonying Siribumrungwong; Peep Talving; Cristian Tranà; Jan Ulrych; Kuo Ching Yuan; Fausto Catena

doi:10.1186/s13017-018-0165-6

Raising concerns about the Sepsis-3 definitions

Massimo Sartelli
, Yoram Kluger
, Luca Ansaloni
, Timothy C. Hardcastle
, Jordi Rello
, Richard R. Watkins
, Matteo Bassetti
, Eleni Giamarellou
, Federico Coccolini
, Fikri M. Abu-Zidan
, Abdulrashid K. Adesunkanmi
, Goran Augustin
, Gian L. Baiocchi
, Miklosh Bala
, Oussema Baraket
, Marcelo A. Beltran
, Asri Che Jusoh
, Zaza Demetrashvili
, Belinda De Simone
, Hamilton P. de Souza

Yunfeng Cui, R. Justin Davies, Sameer Dhingra, Jose J. Diaz, Salomone Di Saverio, Agron Dogjani, Mutasim M. Elmangory, Mushira A. Enani, Paula Ferrada, Gustavo P. Fraga, Sabrina Frattima, Wagih Ghnnam, Carlos A. Gomes, Souha S. Kanj, Aleksandar Karamarkovic, Jakub Kenig, Faryal Khamis, Vladimir Khokha, Kaoru Koike, Kenneth Y.Y. Kok, Arda Isik, Francesco M. Labricciosa, Rifat Latifi, Jae G. Lee, Andrey Litvin, Gustavo M. Machain, Ramiro Manzano-Nunez, Piotr Major, Sanjay Marwah, Michael McFarlane, Ziad A. Memish, Cristian Mesina, Ernest E. Moore, Frederick A. Moore, Noel Naidoo, Ionut Negoi, Richard Ofori-Asenso, Iyiade Olaoye, Carlos A. Ordoñez, Mouaqit Ouadii, Ciro Paolillo, Edoardo Picetti, Tadeja Pintar, Alfredo Ponce-de-Leon, Guntars Pupelis, Tarcisio Reis, Boris Sakakushev, Hossein Samadi Kafil, Norio Sato, Jay N. Shah, Boonying Siribumrungwong, Peep Talving, Cristian Tranà, Jan Ulrych, Kuo Ching Yuan, Fausto Catena

Department of Surgery

Research output: Contribution to journal › Review article › peer-review

96 Citations (Scopus)

Abstract

The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.

Original language	English
Article number	6
Journal	World Journal of Emergency Surgery
Volume	13
Issue number	1
DOIs	https://doi.org/10.1186/s13017-018-0165-6
Publication status	Published - Jan 25 2018

Keywords

Infections
Organ dysfunction
Sepsis
Septic shock

ASJC Scopus subject areas

Surgery
Emergency Medicine

Access to Document

10.1186/s13017-018-0165-6

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Sartelli, M., Kluger, Y., Ansaloni, L., Hardcastle, T. C., Rello, J., Watkins, R. R., Bassetti, M., Giamarellou, E., Coccolini, F., Abu-Zidan, F. M., Adesunkanmi, A. K., Augustin, G., Baiocchi, G. L., Bala, M., Baraket, O., Beltran, M. A., Jusoh, A. C., Demetrashvili, Z., De Simone, B., ... Catena, F. (2018). Raising concerns about the Sepsis-3 definitions. World Journal of Emergency Surgery, 13(1), Article 6. https://doi.org/10.1186/s13017-018-0165-6

Sartelli, M, Kluger, Y, Ansaloni, L, Hardcastle, TC, Rello, J, Watkins, RR, Bassetti, M, Giamarellou, E, Coccolini, F, Abu-Zidan, FM, Adesunkanmi, AK, Augustin, G, Baiocchi, GL, Bala, M, Baraket, O, Beltran, MA, Jusoh, AC, Demetrashvili, Z, De Simone, B, de Souza, HP, Cui, Y, Davies, RJ, Dhingra, S, Diaz, JJ, Di Saverio, S, Dogjani, A, Elmangory, MM, Enani, MA, Ferrada, P, Fraga, GP, Frattima, S, Ghnnam, W, Gomes, CA, Kanj, SS, Karamarkovic, A, Kenig, J, Khamis, F, Khokha, V, Koike, K, Kok, KYY, Isik, A, Labricciosa, FM, Latifi, R, Lee, JG, Litvin, A, Machain, GM, Manzano-Nunez, R, Major, P, Marwah, S, McFarlane, M, Memish, ZA, Mesina, C, Moore, EE, Moore, FA, Naidoo, N, Negoi, I, Ofori-Asenso, R, Olaoye, I, Ordoñez, CA, Ouadii, M, Paolillo, C, Picetti, E, Pintar, T, Ponce-de-Leon, A, Pupelis, G, Reis, T, Sakakushev, B, Kafil, HS, Sato, N, Shah, JN, Siribumrungwong, B, Talving, P, Tranà, C, Ulrych, J, Yuan, KC & Catena, F 2018, 'Raising concerns about the Sepsis-3 definitions', World Journal of Emergency Surgery, vol. 13, no. 1, 6. https://doi.org/10.1186/s13017-018-0165-6

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title = "Raising concerns about the Sepsis-3 definitions",

abstract = "The Global Alliance for Infections in Surgery appreciates the great effort of the task force who derived and validated the Sepsis-3 definitions and considers the new definitions an important step forward in the evolution of our understanding of sepsis. Nevertheless, more than a year after their publication, we have a few concerns regarding the use of the Sepsis-3 definitions.",

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author = "Massimo Sartelli and Yoram Kluger and Luca Ansaloni and Hardcastle, \{Timothy C.\} and Jordi Rello and Watkins, \{Richard R.\} and Matteo Bassetti and Eleni Giamarellou and Federico Coccolini and Abu-Zidan, \{Fikri M.\} and Adesunkanmi, \{Abdulrashid K.\} and Goran Augustin and Baiocchi, \{Gian L.\} and Miklosh Bala and Oussema Baraket and Beltran, \{Marcelo A.\} and Jusoh, \{Asri Che\} and Zaza Demetrashvili and \{De Simone\}, Belinda and \{de Souza\}, \{Hamilton P.\} and Yunfeng Cui and Davies, \{R. Justin\} and Sameer Dhingra and Diaz, \{Jose J.\} and \{Di Saverio\}, Salomone and Agron Dogjani and Elmangory, \{Mutasim M.\} and Enani, \{Mushira A.\} and Paula Ferrada and Fraga, \{Gustavo P.\} and Sabrina Frattima and Wagih Ghnnam and Gomes, \{Carlos A.\} and Kanj, \{Souha S.\} and Aleksandar Karamarkovic and Jakub Kenig and Faryal Khamis and Vladimir Khokha and Kaoru Koike and Kok, \{Kenneth Y.Y.\} and Arda Isik and Labricciosa, \{Francesco M.\} and Rifat Latifi and Lee, \{Jae G.\} and Andrey Litvin and Machain, \{Gustavo M.\} and Ramiro Manzano-Nunez and Piotr Major and Sanjay Marwah and Michael McFarlane and Memish, \{Ziad A.\} and Cristian Mesina and Moore, \{Ernest E.\} and Moore, \{Frederick A.\} and Noel Naidoo and Ionut Negoi and Richard Ofori-Asenso and Iyiade Olaoye and Ordo{\~n}ez, \{Carlos A.\} and Mouaqit Ouadii and Ciro Paolillo and Edoardo Picetti and Tadeja Pintar and Alfredo Ponce-de-Leon and Guntars Pupelis and Tarcisio Reis and Boris Sakakushev and Kafil, \{Hossein Samadi\} and Norio Sato and Shah, \{Jay N.\} and Boonying Siribumrungwong and Peep Talving and Cristian Tran{\`a} and Jan Ulrych and Yuan, \{Kuo Ching\} and Fausto Catena",

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doi = "10.1186/s13017-018-0165-6",

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AU - Sartelli, Massimo

AU - Kluger, Yoram

AU - Ansaloni, Luca

AU - Hardcastle, Timothy C.

AU - Rello, Jordi

AU - Watkins, Richard R.

AU - Bassetti, Matteo

AU - Giamarellou, Eleni

AU - Coccolini, Federico

AU - Abu-Zidan, Fikri M.

AU - Adesunkanmi, Abdulrashid K.

AU - Augustin, Goran

AU - Baiocchi, Gian L.

AU - Bala, Miklosh

AU - Baraket, Oussema

AU - Beltran, Marcelo A.

AU - Jusoh, Asri Che

AU - Demetrashvili, Zaza

AU - De Simone, Belinda

AU - de Souza, Hamilton P.

AU - Cui, Yunfeng

AU - Davies, R. Justin

AU - Dhingra, Sameer

AU - Diaz, Jose J.

AU - Di Saverio, Salomone

AU - Dogjani, Agron

AU - Elmangory, Mutasim M.

AU - Enani, Mushira A.

AU - Ferrada, Paula

AU - Fraga, Gustavo P.

AU - Frattima, Sabrina

AU - Ghnnam, Wagih

AU - Gomes, Carlos A.

AU - Kanj, Souha S.

AU - Karamarkovic, Aleksandar

AU - Kenig, Jakub

AU - Khamis, Faryal

AU - Khokha, Vladimir

AU - Koike, Kaoru

AU - Kok, Kenneth Y.Y.

AU - Isik, Arda

AU - Labricciosa, Francesco M.

AU - Latifi, Rifat

AU - Lee, Jae G.

AU - Litvin, Andrey

AU - Machain, Gustavo M.

AU - Manzano-Nunez, Ramiro

AU - Major, Piotr

AU - Marwah, Sanjay

AU - McFarlane, Michael

AU - Memish, Ziad A.

AU - Mesina, Cristian

AU - Moore, Ernest E.

AU - Moore, Frederick A.

AU - Naidoo, Noel

AU - Negoi, Ionut

AU - Ofori-Asenso, Richard

AU - Olaoye, Iyiade

AU - Ordoñez, Carlos A.

AU - Ouadii, Mouaqit

AU - Paolillo, Ciro

AU - Picetti, Edoardo

AU - Pintar, Tadeja

AU - Ponce-de-Leon, Alfredo

AU - Pupelis, Guntars

AU - Reis, Tarcisio

AU - Sakakushev, Boris

AU - Kafil, Hossein Samadi

AU - Sato, Norio

AU - Shah, Jay N.

AU - Siribumrungwong, Boonying

AU - Talving, Peep

AU - Tranà, Cristian

AU - Ulrych, Jan

AU - Yuan, Kuo Ching

AU - Catena, Fausto

PY - 2018/1/25

Y1 - 2018/1/25

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KW - Infections

KW - Organ dysfunction

KW - Sepsis

KW - Septic shock

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SN - 1749-7922

VL - 13

JO - World Journal of Emergency Surgery

JF - World Journal of Emergency Surgery

IS - 1

M1 - 6

ER -

Raising concerns about the Sepsis-3 definitions

Abstract

Keywords

ASJC Scopus subject areas

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