Recent advances on human mpox

Aliya Orassay; Alan Berdigaliyev; Darya Sadvokassova; Ansal Diassova; Amr Amin; Wenwen Cao; Yingqiu Xie

doi:10.1016/j.nmni.2022.101066

Recent advances on human mpox

Aliya Orassay, Alan Berdigaliyev, Darya Sadvokassova, Ansal Diassova, Amr Amin, Wenwen Cao, Yingqiu Xie

Research output: Contribution to journal › Review article › peer-review

Abstract

Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies showed that current mpox has many genomic mutations related to regulation by APOBEC3. Current mpox has also been suggested to be associated with sexual transmission. Vaccination should be applied and anti-mpox drug should be urgently developed. More investigations are needed to ensure outbreak prevention.

Original language	English
Article number	101066
Journal	New Microbes and New Infections
Volume	51
DOIs	https://doi.org/10.1016/j.nmni.2022.101066
Publication status	Published - Jan 2023

Keywords

Epidemiology
Global health
Infection
Monkeypox
Mpox
Outbreak
Sexual transmission

ASJC Scopus subject areas

Microbiology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.nmni.2022.101066

Cite this

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title = "Recent advances on human mpox",

abstract = "Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies showed that current mpox has many genomic mutations related to regulation by APOBEC3. Current mpox has also been suggested to be associated with sexual transmission. Vaccination should be applied and anti-mpox drug should be urgently developed. More investigations are needed to ensure outbreak prevention.",

keywords = "Epidemiology, Global health, Infection, Monkeypox, Mpox, Outbreak, Sexual transmission",

author = "Aliya Orassay and Alan Berdigaliyev and Darya Sadvokassova and Ansal Diassova and Amr Amin and Wenwen Cao and Yingqiu Xie",

note = "Funding Information: We would like to thank NU FDCRGP grant (110119FD4531, and 11022021FD2920) and UAEU-AUA grant (2019,12R118). We also thank students Didar Zeitkaziyeva and Arailym Myrzagaliyeva for kind help on editing references format. Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2023",

month = jan,

doi = "10.1016/j.nmni.2022.101066",

language = "English",

volume = "51",

journal = "New Microbes and New Infections",

issn = "2052-2975",

publisher = "Elsevier BV",

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T1 - Recent advances on human mpox

AU - Orassay, Aliya

AU - Berdigaliyev, Alan

AU - Sadvokassova, Darya

AU - Diassova, Ansal

AU - Amin, Amr

AU - Cao, Wenwen

AU - Xie, Yingqiu

N1 - Funding Information: We would like to thank NU FDCRGP grant (110119FD4531, and 11022021FD2920) and UAEU-AUA grant (2019,12R118). We also thank students Didar Zeitkaziyeva and Arailym Myrzagaliyeva for kind help on editing references format. Publisher Copyright: © 2022 The Authors

PY - 2023/1

Y1 - 2023/1

N2 - Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies showed that current mpox has many genomic mutations related to regulation by APOBEC3. Current mpox has also been suggested to be associated with sexual transmission. Vaccination should be applied and anti-mpox drug should be urgently developed. More investigations are needed to ensure outbreak prevention.

AB - Mpox has been a concern of public health and travel caution. Using databases of WHO, CDC, google scholar, and PubMed, we searched recent literatures and reviewed the history, genomic mutation/evolution, host cell response pathways, regulation policy, vaccine and therapy development. Recent studies showed that current mpox has many genomic mutations related to regulation by APOBEC3. Current mpox has also been suggested to be associated with sexual transmission. Vaccination should be applied and anti-mpox drug should be urgently developed. More investigations are needed to ensure outbreak prevention.

KW - Epidemiology

KW - Global health

KW - Infection

KW - Monkeypox

KW - Mpox

KW - Outbreak

KW - Sexual transmission

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DO - 10.1016/j.nmni.2022.101066

M3 - Review article

AN - SCOPUS:85147574604

SN - 2052-2975

VL - 51

JO - New Microbes and New Infections

JF - New Microbes and New Infections

M1 - 101066

ER -

Recent advances on human mpox

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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