Recent Developments in Starch-Based Delivery Systems of Bioactive Compounds: Formulations and Applications

Sadia Aslam, Aqsa Akhtar, Nilesh Nirmal, Nauman Khalid, Sajid Maqsood

    Research output: Contribution to journalReview articlepeer-review

    14 Citations (Scopus)

    Abstract

    Bioactive compounds exhibit numerous health benefits; however, they are highly sensitive to degradation under various process conditions. Applications of these compounds are limited in food and pharmaceutical products due to their quick release, low solubility, possible interactions with other ingredients, and reduced biological potential. Encapsulation in suitable carrier systems could protect their bioactivity and retain sensorial properties of products during processing and storage. Starch is a natural polysaccharide, and its physicochemical properties offer an excellent carrier system for various bioactive compounds. In this review, comprehensive discussions have been provided on the different fabrication techniques of starch-based micro, nano-carrier systems and their applications for various bioactive compounds have been discussed also. Various techniques including nano-spray drying, electrospinning, extrusion, acid hydrolysis, nanoemulsification, nanoprecipitation, microfluidization, ultrasonication, and gamma-irradiation have been employed to fabricate micro and nanocarrier systems from a starch biopolymer. Starch-based nanostructures are emerging as a novel and promising nano-vehicles for delivering bioactive compounds.

    Original languageEnglish
    Pages (from-to)271-291
    Number of pages21
    JournalFood Engineering Reviews
    Volume14
    Issue number2
    DOIs
    Publication statusPublished - Jun 2022

    Keywords

    • Biopolymers
    • Encapsulation
    • Nanostructures
    • Starch nanoparticles

    ASJC Scopus subject areas

    • Industrial and Manufacturing Engineering

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