Remodelling of the neuromuscular junction after subtotal disuse

M. A. Fahim, N. Robbins

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


Within 5 days after reduction of activity of the rat soleus muscle, there was remodelling of the neuromuscular junction. Post-synaptic clefts were shorter, wider, and flatter, whereas nerve terminals showed sprouting and longitudinal distortion. The results, which differ from those found after denervation or total disuse, reveal the plasticity of the mature neuromuscular synapse.

Original languageEnglish
Pages (from-to)353-356
Number of pages4
JournalBrain Research
Issue number1-2
Publication statusPublished - Sept 24 1986
Externally publishedYes


  • Muscle disuse
  • Muscle innervation
  • Nerve terminal
  • Neuromuscular junction
  • Neuromuscular remodelling
  • Synaptic plasticity

ASJC Scopus subject areas

  • General Neuroscience
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology


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