The growth in the use of cellular phone has raised concerns about the possible interaction between electromagnetic fields (EMF) radiation and the effects on human tissues, particularly the and the human immune system. These concerns induced a large volume of research studies. , most of the previous review studies are on negative effects and no published took in consideration all possible effects caused the use of cell phones. In this paper we aim to review of some studies which investigated the negative and positive biological effects of cell radiation on human tissues. This review will answers for public concerns about the risk of cell phone. Our conclusion shows that long-term to EMF radiation from a cell phone could health effects, such as brain cancer. Some health effects due to the exposure to the EMF such as improve bone healing and reduce effects of chemotherapy are highlighted. Finally, studies have also showed no effect due to to EMF. More long-term studies and analysis are much needed.