Resistance patterns of bacterial isolates to antimicrobials from 3 hospitals in the United Arab Emirates

Ahmed S. Al-Dhaheri, Mohammed S. Al-Niyadi, Ahmed Al-Dhaheri, Salim M. Bastaki

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

Objective: To compare the resistance pattern of common bacterial pathogens to commonly used drugs. Methods: Information and statistics of antimicrobial resistance for 1994 and 2005 were collected from the 3 hospital microbiology laboratories in the United Arab Emirates. The resistance patterns of Staphylococcus aureus, Escherichia coli, Klebsiella spp, and Pseudomonas aeruginosa to several front-line drugs were estimated. All laboratories used automatic machines (Vitek 2), which identifies and determines minimum inhibitory concentrations simultaneously. Results: Increased resistance was observed for Staphylococcus aureus, (n=315, 2005) to erythromycin (approximately 6 fold, Al-Ain Hospital only), cloxacillin (Al-Ain Hospital), and gentamicin (more than 3-10 folds in all hospitals). Increased penicillin resistance was not observed. For the common gram-negative organisms, there was a high resistance to ampicillin, gentamicin, ceftriaxone, ciprofloxacin, and imipenem, which seemed to increase for Escherichia coli, (by 4.2-200%, n=305, 2005); however, there was very little resistance to imipenem (0.4%) in Tawam Hospital. Variable resistance patterns were obtained for Pseudomonas aeruginosa (n=316, 2005) and Klebsiella spp, (n=316, 2005) against aminoglycosides, cephalosporins, ciprofloxacin, and norfloxacin. Conclusion: Overall, there was an obvious increase in resistance of bacteria and the prevalence rate to a number of drugs from 1-120 folds during the 11-year period.

Original languageEnglish
Pages (from-to)618-623
Number of pages6
JournalSaudi Medical Journal
Volume30
Issue number5
Publication statusPublished - 2009

ASJC Scopus subject areas

  • General Medicine

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