Role of fruits in aging and age-related disorders

Muhammad Usman Arif, Muhammad Kashif Iqbal Khan, Sana Riaz, Akmal Nazir, Abid Aslam Maan, Usman Amin, Farhan Saeed, Muhammad Afzaal

    Research output: Contribution to journalReview articlepeer-review

    1 Citation (Scopus)

    Abstract

    Aging is a collection of changes that contribute to decline in maximum function and ultimately death of an organism. This process is controlled and initiated by several mechanisms including telomere shortening, oxidative stress, AMP-activated protein kinase and sirt-1. Several therapies have been reported to relieve the process of aging. Among these, diet therapy seems to be the most appropriate approach. Fruits are an important part of regular diet. They contain several compounds which have potential to handle the problem of aging and its related disorders. The present paper provides a comprehensive review on different factors present in various fruits related to the process of aging together with their antiaging mechanisms.

    Original languageEnglish
    Article number111763
    JournalExperimental Gerontology
    Volume162
    DOIs
    Publication statusPublished - Jun 1 2022

    Keywords

    • Aging
    • AMPK
    • Oxidative stress
    • Reactive oxygen spices
    • Sirt 1
    • Telomere

    ASJC Scopus subject areas

    • Biochemistry
    • Ageing
    • Molecular Biology
    • Genetics
    • Endocrinology
    • Cell Biology

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