Role of fruits in aging and age-related disorders

Muhammad Usman Arif; Muhammad Kashif Iqbal Khan; Sana Riaz; Akmal Nazir; Abid Aslam Maan; Usman Amin; Farhan Saeed; Muhammad Afzaal

doi:10.1016/j.exger.2022.111763

Role of fruits in aging and age-related disorders

Muhammad Usman Arif, Muhammad Kashif Iqbal Khan, Sana Riaz, Akmal Nazir, Abid Aslam Maan, Usman Amin, Farhan Saeed, Muhammad Afzaal

Research output: Contribution to journal › Review article › peer-review

4 Citations (Scopus)

Abstract

Aging is a collection of changes that contribute to decline in maximum function and ultimately death of an organism. This process is controlled and initiated by several mechanisms including telomere shortening, oxidative stress, AMP-activated protein kinase and sirt-1. Several therapies have been reported to relieve the process of aging. Among these, diet therapy seems to be the most appropriate approach. Fruits are an important part of regular diet. They contain several compounds which have potential to handle the problem of aging and its related disorders. The present paper provides a comprehensive review on different factors present in various fruits related to the process of aging together with their antiaging mechanisms.

Original language	English
Article number	111763
Journal	Experimental Gerontology
Volume	162
DOIs	https://doi.org/10.1016/j.exger.2022.111763
Publication status	Published - Jun 1 2022

Keywords

Aging
AMPK
Oxidative stress
Reactive oxygen spices
Sirt 1
Telomere

ASJC Scopus subject areas

Biochemistry
Ageing
Molecular Biology
Genetics
Endocrinology
Cell Biology

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10.1016/j.exger.2022.111763

Cite this

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title = "Role of fruits in aging and age-related disorders",

abstract = "Aging is a collection of changes that contribute to decline in maximum function and ultimately death of an organism. This process is controlled and initiated by several mechanisms including telomere shortening, oxidative stress, AMP-activated protein kinase and sirt-1. Several therapies have been reported to relieve the process of aging. Among these, diet therapy seems to be the most appropriate approach. Fruits are an important part of regular diet. They contain several compounds which have potential to handle the problem of aging and its related disorders. The present paper provides a comprehensive review on different factors present in various fruits related to the process of aging together with their antiaging mechanisms.",

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AU - Arif, Muhammad Usman

AU - Khan, Muhammad Kashif Iqbal

AU - Riaz, Sana

AU - Nazir, Akmal

AU - Maan, Abid Aslam

AU - Amin, Usman

AU - Saeed, Farhan

AU - Afzaal, Muhammad

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AB - Aging is a collection of changes that contribute to decline in maximum function and ultimately death of an organism. This process is controlled and initiated by several mechanisms including telomere shortening, oxidative stress, AMP-activated protein kinase and sirt-1. Several therapies have been reported to relieve the process of aging. Among these, diet therapy seems to be the most appropriate approach. Fruits are an important part of regular diet. They contain several compounds which have potential to handle the problem of aging and its related disorders. The present paper provides a comprehensive review on different factors present in various fruits related to the process of aging together with their antiaging mechanisms.

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KW - AMPK

KW - Oxidative stress

KW - Reactive oxygen spices

KW - Sirt 1

KW - Telomere

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Role of fruits in aging and age-related disorders

Abstract

Keywords

ASJC Scopus subject areas

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