ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine

Medicine & Life Sciences

• sanguinarine 88%
• Autophagy 50%
• Glioma 48%
• Autophagic Cell Death 44%
• Reactive Oxygen Species 42%
• N-acetylglutathione 7%
• Cell Death 6%
• bafilomycin A1 6%
• Autophagy-Related Proteins 6%
• Beclin-1 5%
• U 0126 5%
• Prodrugs 4%
• Pyruvic Acid 4%
• Drug Delivery Systems 4%
• Catalase 4%
• Organelles 4%
• Cysteine 4%
• Sodium 3%
• Antioxidants 3%
• Down-Regulation 3%
• Neoplasms 2%
• Apoptosis 2%
• Cell Line 2%
• Therapeutics 2%
• In Vitro Techniques 1%
• Proteins 1%

Chemical Compounds

• Anti Glioma 100%
• Sanguinarine 82%
• Cell Death 55%
• Dioxygen 25%
• U0126 11%
• Autophagy Inhibitor 11%
• Reactive Oxygen Metabolite 10%
• Bafilomycin A1 9%
• Sodium Pyruvate 9%
• Apoptotic 6%
• Drug 6%
• Glutathione 5%
• Cysteine 5%
• Protein 4%
• Antioxidant Agent 4%