Abstract
In survival clinical trials the response, i.e. (time to) death is delayed. As a result there are at any time patients that have not responded, yet. Given a stopping rule based on the number of deaths, the distribution of the total number of patients that will enter the trial is examined. Besides, a simple approximation to the expected number of patients is presented.
| Original language | English |
|---|---|
| Pages (from-to) | 709-714 |
| Number of pages | 6 |
| Journal | Biometrical Journal |
| Volume | 23 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1981 |
| Externally published | Yes |
ASJC Scopus subject areas
- Statistics and Probability
- Statistics, Probability and Uncertainty