Selective One-Pot Multicomponent Synthesis of N-Substituted 2,3,5-Functionalized 3-Cyanopyrroles via the Reaction between α-Hydroxyketones, Oxoacetonitriles, and Primary Amines

Chemical Compounds

• Pyrroles 73%
• Primary Amine 62%
• Pyrrole 60%
• Multicomponent Reaction 56%
• Single Crystal X-Ray Diffraction 47%
• Catalyst 26%
• Reaction Yield 26%
• Molecule 22%

Physics & Astronomy

• amines 76%
• synthesis 46%
• pyrroles 30%
• activity (biology) 13%
• entry 11%
• selectivity 10%
• catalysts 10%
• nuclear magnetic resonance 8%
• single crystals 6%
• water 6%
• molecules 5%
• diffraction 5%
• atoms 5%
• x rays 4%

Medicine & Life Sciences

• Pyrroles 100%
• Amines 68%
• X-Ray Diffraction 38%
• Water 21%