Semi-empirical Modeling for DNA Nucleotides via Silicon Nanowire Field-effect Transistor Sensor with a Nanogap

Asma Wasfi, Nisreen Alnaji, Falah Awwad

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Lately, Silicon Nanowire field-effect transistor have attracted massive attention, due to its high-sensitivity, selectivity, label-free and real-time detection capabilities. DNA detection has obtained significance increasingly through the years. Here, a novel Silicon Nanowire field-effect transistor sensor with a nanogap placed in the middle of the sensor is studied for DNA nucleotides detection purpose. The sensor results in a distinct electronic signature for each of the different DNA nucleotides (Adenosine, Guanosine Thymidine, and Cytidine). Semi-empirical model integrated with non-equilibrium Green's function is used to analyze the DNA nucleotides detection process. The results indicate that the developed sensor could promote a novel sensing of DNA nucleotides with high accuracy.

Original languageEnglish
Title of host publication2022 International Conference on Microelectronics, ICM 2022
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages12-15
Number of pages4
ISBN (Electronic)9781665493246
DOIs
Publication statusPublished - 2022
Event2022 International Conference on Microelectronics, ICM 2022 - Virtual, Online, Morocco
Duration: Dec 4 2022Dec 7 2022

Publication series

Name2022 International Conference on Microelectronics, ICM 2022

Conference

Conference2022 International Conference on Microelectronics, ICM 2022
Country/TerritoryMorocco
CityVirtual, Online
Period12/4/2212/7/22

Keywords

  • DNA sequencing
  • electronic properties
  • nanogap
  • semi-empirical modeling
  • silicon nanowire field-effect transistor

ASJC Scopus subject areas

  • Artificial Intelligence
  • Computer Networks and Communications
  • Hardware and Architecture
  • Information Systems
  • Electrical and Electronic Engineering
  • Health Informatics
  • Instrumentation

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