TY - JOUR
T1 - Seroprevalence of Toxoplasma gondii and Neospora caninum infections in cattle in Mongolia
AU - Pagmadulam, Baldorj
AU - Myagmarsuren, Punsantsogvoo
AU - Fereig, Ragab M.
AU - Igarashi, Makoto
AU - Yokoyama, Naoaki
AU - Battsetseg, Badgar
AU - Nishikawa, Yoshifumi
N1 - Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2018/12
Y1 - 2018/12
N2 - Toxoplasma gondii and Neospora caninum are protozoan parasites that cause huge economic losses in animal industries worldwide. N. caninum can cause abortion storms and high culling rates in cattle, whereas T. gondii infection is a significant concern in both human and animals because it can induce abortion and clinical symptoms in immunocompromised hosts. The aim of this study was to determine the seroprevalence of T. gondii and N. caninum in cattle in Mongolia. Specific antibodies to T. gondii and N. caninum were detected by using an indirect enzyme-linked immunosorbent assay (iELISA) based on recombinant antigens of dense granule protein 7 of Toxoplasma gondii and surface antigen 1 of Neospora caninum, respectively. A total of 1438 cattle sera from 20 of 21 provinces of Mongolia and the capital city of Ulaanbaatar were tested. Overall, 18.7% and 26.2% of cattle were positive for specific antibodies to T. gondii and N. caninum, respectively. Prevalence rates were higher (T. gondii infection: P <.0001, N. caninum infection: P =.002) in the central region of Mongolia (T. gondii infection: 27.1%, N. caninum infection: 30.8%) compared with western region, suggesting that prevalence rates might be influenced by geographical condition, particularly warmer temperatures around this area in Mongolia. The lowest prevalence rates were observed in the western region of Mongolia (T. gondii: 9%, N. caninum: 20.8%). In addition, the seroprevalence of N. caninum in female animals (27.5%) was significantly higher than that in male animals (20.4%) (P =.018), suggesting an important risk factor of abortion and stillbirth in cattle. The present results showed that T. gondii and N. caninum infections might be a risk for public health and economy of the livestock industry in Mongolia. In conclusion, this study demonstrates high seroprevalences of T. gondii and N. caninum in Mongolia and provides valuable new data for development of control measures against these infections in Mongolia.
AB - Toxoplasma gondii and Neospora caninum are protozoan parasites that cause huge economic losses in animal industries worldwide. N. caninum can cause abortion storms and high culling rates in cattle, whereas T. gondii infection is a significant concern in both human and animals because it can induce abortion and clinical symptoms in immunocompromised hosts. The aim of this study was to determine the seroprevalence of T. gondii and N. caninum in cattle in Mongolia. Specific antibodies to T. gondii and N. caninum were detected by using an indirect enzyme-linked immunosorbent assay (iELISA) based on recombinant antigens of dense granule protein 7 of Toxoplasma gondii and surface antigen 1 of Neospora caninum, respectively. A total of 1438 cattle sera from 20 of 21 provinces of Mongolia and the capital city of Ulaanbaatar were tested. Overall, 18.7% and 26.2% of cattle were positive for specific antibodies to T. gondii and N. caninum, respectively. Prevalence rates were higher (T. gondii infection: P <.0001, N. caninum infection: P =.002) in the central region of Mongolia (T. gondii infection: 27.1%, N. caninum infection: 30.8%) compared with western region, suggesting that prevalence rates might be influenced by geographical condition, particularly warmer temperatures around this area in Mongolia. The lowest prevalence rates were observed in the western region of Mongolia (T. gondii: 9%, N. caninum: 20.8%). In addition, the seroprevalence of N. caninum in female animals (27.5%) was significantly higher than that in male animals (20.4%) (P =.018), suggesting an important risk factor of abortion and stillbirth in cattle. The present results showed that T. gondii and N. caninum infections might be a risk for public health and economy of the livestock industry in Mongolia. In conclusion, this study demonstrates high seroprevalences of T. gondii and N. caninum in Mongolia and provides valuable new data for development of control measures against these infections in Mongolia.
KW - Cattle
KW - Mongolia
KW - Neospora caninum
KW - Seroprevalence
KW - Toxoplasma gondii
UR - https://www.scopus.com/pages/publications/85051968155
UR - https://www.scopus.com/pages/publications/85051968155#tab=citedBy
U2 - 10.1016/j.vprsr.2018.08.001
DO - 10.1016/j.vprsr.2018.08.001
M3 - Article
C2 - 31014714
AN - SCOPUS:85051968155
SN - 0304-4017
VL - 14
SP - 11
EP - 17
JO - Veterinary Parasitology: Regional Studies and Reports
JF - Veterinary Parasitology: Regional Studies and Reports
ER -
