Abstract
Aim: This study aimed to investigate whether serum biochemical parameters can be used as a surrogate for chest computed tomography (CT) in the diagnosis of COVID-19 in pediatric patients. Materials & methods: We evaluated potential associations between various serum biochemical markers and the COVID-reporting and data system (RADS) pneumonia grading system in 53 individuals with confirmed COVID-19. Results: A total of 28 chest CT scans (52.8%) were abnormal. Patients with confirmed COVID-19 on CT showed a statistically significant increase in lactate dehydrogenase (186.4 ± 56.5 vs 228.4 ± 60.6; p = 0.01), which was significantly correlated with the COVID-RADS pneumonia grading system. Conclusion: Lactate dehydrogenase can be used as a surrogate marker for chest CT in children with COVID-19. This can reduce exposure to ionizing radiation during initial diagnostic procedures in children with suspected COVID-19 pneumonia.
Original language | English |
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Pages (from-to) | 601-609 |
Number of pages | 9 |
Journal | Future Virology |
Volume | 16 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sept 2021 |
Keywords
- COVID-19
- Chest CT
- LDH
- serum ferritin
ASJC Scopus subject areas
- Virology