Silicotungstic acid as a highly efficient coreactant for luminol chemiluminescence for sensitive detection of uric acid

Islam M. Mostafa, Mohamed Ibrahim Halawa, Yequan Chen, Abubakar Abdussalam, Yiran Guan, Guobao Xu

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Herein, we report luminol-silicotungstic acid (STA) chemiluminescence (CL) for the first time. The luminol-STA system resulted in remarkable CL enhancement (65 times) compared with the known classical luminol-H2O2 system because of the generation of the strong oxidizing agent tungsten trioxide from STA. Based on the quenching effect of uric acid, the new CL system is applied for the sensitive and selective assay of uric acid in its pure state (LOD 0.75 nM) and in real human urine with excellent recoveries in the range of 99.6-102.3%. Furthermore, this system permits the efficient detection of STA (LOD, 0.24 μM).

Original languageEnglish
Pages (from-to)2709-2715
Number of pages7
JournalAnalyst
Volume145
Issue number7
DOIs
Publication statusPublished - Apr 7 2020
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Environmental Chemistry
  • Spectroscopy
  • Electrochemistry

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