TY - JOUR
T1 - Space-time cluster analysis of invasive meningococcal disease
AU - Hoebe, Christian J.P.A.
AU - De Melker, Hester
AU - Spanjaard, Lodewijk
AU - Dankert, Jacob
AU - Nagelkerke, Nico
PY - 2004/9
Y1 - 2004/9
N2 - Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993-2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%).
AB - Clusters are recognized when meningococcal cases of the same phenotypic strain (markers: serogroup, serotype, and subtype) occur in spatial and temporal proximity. The incidence of such clusters was compared to the incidence that would be expected by chance by using space-time nearest-neighbor analysis of 4,887 confirmed invasive meningococcal cases identified in the 9-year surveillance period 1993-2001 in the Netherlands. Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%).
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U2 - 10.3201/eid1009.030992
DO - 10.3201/eid1009.030992
M3 - Article
C2 - 15498165
AN - SCOPUS:4444243391
SN - 1080-6040
VL - 10
SP - 1621
EP - 1626
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 9
ER -