Stereoselective synthesis of alicylic amines

Kristoffer F. Graham; Kenneth T. Hindle; S. David Jackson; David J.M. Williams; Stefan Wuttke

doi:10.1007/s11244-010-9544-2

Stereoselective synthesis of alicylic amines

Kristoffer F. Graham, Kenneth T. Hindle, S. David Jackson, David J.M. Williams, Stefan Wuttke

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The hydrogenation 4-alkylanilines over Rh/silica catalysts display an antipathetic particle size effect suggesting that the active site is a terrace face. The effect of the solvent on product cis:trans ratio was related to polar solvents stabilising an imine intermediate. The products inhibited the reaction due to their increased basicity which allowed a strong metal-nitrogen interaction.

Original language	English
Pages (from-to)	1121-1125
Number of pages	5
Journal	Topics in Catalysis
Volume	53
Issue number	15-18
DOIs	https://doi.org/10.1007/s11244-010-9544-2
Publication status	Published - Sept 2010
Externally published	Yes

Keywords

Aromatic amine hydrogenation
Deactivation
Rhodium
Selectivity

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1007/s11244-010-9544-2

Cite this

@article{143f85aaf9a446e0ab23c8864c85b558,

title = "Stereoselective synthesis of alicylic amines",

abstract = "The hydrogenation 4-alkylanilines over Rh/silica catalysts display an antipathetic particle size effect suggesting that the active site is a terrace face. The effect of the solvent on product cis:trans ratio was related to polar solvents stabilising an imine intermediate. The products inhibited the reaction due to their increased basicity which allowed a strong metal-nitrogen interaction.",

keywords = "Aromatic amine hydrogenation, Deactivation, Rhodium, Selectivity",

author = "Graham, {Kristoffer F.} and Hindle, {Kenneth T.} and {David Jackson}, S. and Williams, {David J.M.} and Stefan Wuttke",

year = "2010",

month = sep,

doi = "10.1007/s11244-010-9544-2",

language = "English",

volume = "53",

pages = "1121--1125",

journal = "Topics in Catalysis",

issn = "1022-5528",

publisher = "Springer",

number = "15-18",

}

TY - JOUR

T1 - Stereoselective synthesis of alicylic amines

AU - Graham, Kristoffer F.

AU - Hindle, Kenneth T.

AU - David Jackson, S.

AU - Williams, David J.M.

AU - Wuttke, Stefan

PY - 2010/9

Y1 - 2010/9

N2 - The hydrogenation 4-alkylanilines over Rh/silica catalysts display an antipathetic particle size effect suggesting that the active site is a terrace face. The effect of the solvent on product cis:trans ratio was related to polar solvents stabilising an imine intermediate. The products inhibited the reaction due to their increased basicity which allowed a strong metal-nitrogen interaction.

AB - The hydrogenation 4-alkylanilines over Rh/silica catalysts display an antipathetic particle size effect suggesting that the active site is a terrace face. The effect of the solvent on product cis:trans ratio was related to polar solvents stabilising an imine intermediate. The products inhibited the reaction due to their increased basicity which allowed a strong metal-nitrogen interaction.

KW - Aromatic amine hydrogenation

KW - Deactivation

KW - Rhodium

KW - Selectivity

UR - http://www.scopus.com/inward/record.url?scp=78651072136&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78651072136&partnerID=8YFLogxK

U2 - 10.1007/s11244-010-9544-2

DO - 10.1007/s11244-010-9544-2

M3 - Article

AN - SCOPUS:78651072136

SN - 1022-5528

VL - 53

SP - 1121

EP - 1125

JO - Topics in Catalysis

JF - Topics in Catalysis

IS - 15-18

ER -

Stereoselective synthesis of alicylic amines

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this