TY - GEN
T1 - SubSS
T2 - 6th IEEE/ACIS International Conference on Computer and Information Science, ICIS 2007; 1st IEEE/ACIS International Workshop on e-Activity, IWEA 2007
AU - Zaki, Nazar
AU - Deris, Safaai
AU - Alwahaishi, Saleh
PY - 2007
Y1 - 2007
N2 - Many essential cellular processes are mediated by protein-protein interaction the reason why predicting protein-protein interaction has recently received considerable attention from biologist around the globe. In this paper, we present a computational tool for detecting protein-protein interaction based on substring similarity measure. Two proteins may interact by the mean of the similarities of the substrings they contain. This friendly and easy to use tool helps biologist to distinguish between high confidence interactions from low confidence or unknown interactions. The tool performance is tested on the currently available protein-protein interaction data for the yeast Saccharomyces cerevisiae, and it delivered considerable improvement over the existing techniques.
AB - Many essential cellular processes are mediated by protein-protein interaction the reason why predicting protein-protein interaction has recently received considerable attention from biologist around the globe. In this paper, we present a computational tool for detecting protein-protein interaction based on substring similarity measure. Two proteins may interact by the mean of the similarities of the substrings they contain. This friendly and easy to use tool helps biologist to distinguish between high confidence interactions from low confidence or unknown interactions. The tool performance is tested on the currently available protein-protein interaction data for the yeast Saccharomyces cerevisiae, and it delivered considerable improvement over the existing techniques.
UR - http://www.scopus.com/inward/record.url?scp=46749153058&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=46749153058&partnerID=8YFLogxK
U2 - 10.1109/ICIS.2007.175
DO - 10.1109/ICIS.2007.175
M3 - Conference contribution
AN - SCOPUS:46749153058
SN - 0769528414
SN - 9780769528410
T3 - Proceedings - 6th IEEE/ACIS International Conference on Computer and Information Science, ICIS 2007; 1st IEEE/ACIS International Workshop on e-Activity, IWEA 2007
SP - 999
EP - 1004
BT - Proceedings - 6th IEEE/ACIS International Conference on Computer and Information Science, ICIS 2007; 1st IEEE/ACIS International Workshop on e-Activity, IWEA 2007
Y2 - 11 July 2007 through 13 July 2007
ER -