Successful Management of a Unique Condition of Isolated Intracranial Mucormycosis in an Immunocompetent Child

Mohammed M. Al Barbarawi, Mohammed Z. Allouh

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

This report describes a unique case of isolated intracranial mucormycosis of a slowly progressive nature in a healthy immunocompetent child. A 4-year-old girl with a clear medical and surgical history presented with complaints of right side facial asymmetry and unsteady gait for a period of 10 months. Clinical and radiographic investigations revealed right-sided lower motor neuron facial palsy caused by an infiltrative lesion on the right cerebellopontine angle. Initial surgical debulking was performed, a biopsy was sent for histopathological examination, and a course of prophylactic antibiotic and antifungal drugs was prescribed. The pathological report confirmed the mucormycosis fungal infection, and intravenous amphotericin B was administered for 3 weeks. One month after admission, the patient left the hospital with complete recovery. Follow-ups after 4, 8 and 12 weeks revealed no sensory or motor neurological deficits. In conclusion, this is a unique case of mucormycosis with regard to the nature and location of the infection, along with the host being a healthy child. Initial surgical exploration is a very critical step in the early diagnosis and treatment of such rare conditions.

Original languageEnglish
Pages (from-to)165-167
Number of pages3
JournalPediatric Neurosurgery
Volume50
Issue number3
DOIs
Publication statusPublished - Jul 22 2015
Externally publishedYes

Keywords

  • Amphotericin B
  • Fungal infection
  • Immunocompetence
  • Indolence
  • Mucormycosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Clinical Neurology

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