TY - JOUR
T1 - Survey of antibiotic use of individuals visiting public healthcare facilities in Indonesia
AU - Hadi, Usman
AU - Duerink, D. Offra
AU - Lestari, Endang Sri
AU - Nagelkerke, Nico J.
AU - Werter, Susanne
AU - Keuter, Monique
AU - Suwandojo, Eddy
AU - Rahardjo, Eddy
AU - van den Broek, Peterhans
AU - Gyssens, Inge C.
N1 - Funding Information:
Financial support was provided by the Royal Netherlands Academy of Arts and Sciences within the framework of the Scientific Programme Indonesia–The Netherlands (SPIN1).
PY - 2008/11
Y1 - 2008/11
N2 - Objectives: To estimate the antibiotic use of individuals visiting public healthcare facilities in Indonesia and to identify determinants of use against a background of high resistance rates. Methods: Patients on admission to hospital (group A), visiting a primary health center (group B), and healthy relatives (group C) were included in the study. A questionnaire on demographic, socioeconomic, and healthcare-related items including health complaints and consumption of antibiotics was used. Logistic regression was performed to determine the co-variables of antibiotic use. Results: Of 2996 individuals interviewed, 486 (16%) had taken an antibiotic. Compared to group C (7% consumption), groups B and A exhibited a three-fold and four-fold higher use of antibiotics, respectively. Respiratory (80%) and gastrointestinal (13%) symptoms were most frequent. Aminopenicillins and tetracyclines accounted for 80% of the prescribed antibiotics. Similar antibiotics were self-medicated (17% of users). Age less than 18 years and health insurance were independent determinants of antibiotic use. Urban provenance, being adult, male, and having no health insurance were independent determinants of self-medication. Conclusions: In addition to health complaints, other factors determined antibiotic consumption. In view of the likely viral origin of respiratory complaints and the resistance of intestinal pathogens, most antibiotic use was probably unnecessary or ineffective. Future interventions should be directed towards healthcare providers.
AB - Objectives: To estimate the antibiotic use of individuals visiting public healthcare facilities in Indonesia and to identify determinants of use against a background of high resistance rates. Methods: Patients on admission to hospital (group A), visiting a primary health center (group B), and healthy relatives (group C) were included in the study. A questionnaire on demographic, socioeconomic, and healthcare-related items including health complaints and consumption of antibiotics was used. Logistic regression was performed to determine the co-variables of antibiotic use. Results: Of 2996 individuals interviewed, 486 (16%) had taken an antibiotic. Compared to group C (7% consumption), groups B and A exhibited a three-fold and four-fold higher use of antibiotics, respectively. Respiratory (80%) and gastrointestinal (13%) symptoms were most frequent. Aminopenicillins and tetracyclines accounted for 80% of the prescribed antibiotics. Similar antibiotics were self-medicated (17% of users). Age less than 18 years and health insurance were independent determinants of antibiotic use. Urban provenance, being adult, male, and having no health insurance were independent determinants of self-medication. Conclusions: In addition to health complaints, other factors determined antibiotic consumption. In view of the likely viral origin of respiratory complaints and the resistance of intestinal pathogens, most antibiotic use was probably unnecessary or ineffective. Future interventions should be directed towards healthcare providers.
KW - Antibiotic policy
KW - Antimicrobial agents
KW - Community
KW - Resistance
KW - Self-medication
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U2 - 10.1016/j.ijid.2008.01.002
DO - 10.1016/j.ijid.2008.01.002
M3 - Article
C2 - 18396084
AN - SCOPUS:54349114097
SN - 1201-9712
VL - 12
SP - 622
EP - 629
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
IS - 6
ER -