Synthesis and characterization of chitosan-coated magnetite nanoparticles using a modified wet method for drug delivery applications

Rkia El-kharrag, Sulafa S. Abdel Halim, Amr Amin, Yaser E. Greish

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

Immobilizing various chemical functionalities on the surfaces of magnetite nanoparticles extends these applications without affecting the overall magnetic properties of the coated nanoparticles. In this study, magnetite nanoparticles have been prepared in the presence of chitosan using a simple modified wet method. Composition, morphology and magnetic properties of the chitosan-coated nanoparticles were investigated. Results showed the formation of coating with various thicknesses on the surfaces of the superparamagnetic nanoparticles. This in turn reduced the magnetization of the nanoparticles to some extent. The least particle size obtained in the presence of chitosan was 10 nm.

Original languageEnglish
Pages (from-to)73-82
Number of pages10
JournalInternational Journal of Polymeric Materials and Polymeric Biomaterials
Volume68
Issue number1-3
DOIs
Publication statusPublished - Feb 11 2019

Keywords

  • Magnetite
  • chitosan
  • coatings
  • magnetic properties
  • microstructure
  • nano-modified surfaces

ASJC Scopus subject areas

  • Analytical Chemistry
  • General Chemical Engineering
  • Polymers and Plastics

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