Synthesis of 5-amino-3,3-dimethyl-7-phenyl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides

Mourad Chioua; Abdelouahid Samadi; Denis Postel; Jan Balzarini; José Marco-Contelles

doi:10.1002/jhet.1678

Synthesis of 5-amino-3,3-dimethyl-7-phenyl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides

Mourad Chioua
, Abdelouahid Samadi
, Denis Postel
, Jan Balzarini
, José Marco-Contelles

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

The reaction of 4-amino-5,5-dimethyl-5H-1,2-oxathiole 2,2-dioxide (1) with 2-(arylidene)malononitriles 2 in ethanol, at reflux, using piperidine as catalyst, afforded 5-amino-3,3-dimethyl-7-aryl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides (3) in moderate chemical yields.

Original language	English
Pages (from-to)	1452-1456
Number of pages	5
Journal	Journal of Heterocyclic Chemistry
Volume	51
Issue number	5
DOIs	https://doi.org/10.1002/jhet.1678
Publication status	Published - Sept 1 2014
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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title = "Synthesis of 5-amino-3,3-dimethyl-7-phenyl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides",

abstract = "The reaction of 4-amino-5,5-dimethyl-5H-1,2-oxathiole 2,2-dioxide (1) with 2-(arylidene)malononitriles 2 in ethanol, at reflux, using piperidine as catalyst, afforded 5-amino-3,3-dimethyl-7-aryl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides (3) in moderate chemical yields.",

author = "Mourad Chioua and Abdelouahid Samadi and Denis Postel and Jan Balzarini and Jos{\'e} Marco-Contelles",

note = "Publisher Copyright: {\textcopyright} 2014 HeteroCorporation.",

year = "2014",

month = sep,

day = "1",

doi = "10.1002/jhet.1678",

language = "English",

volume = "51",

pages = "1452--1456",

journal = "Journal of Heterocyclic Chemistry",

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TY - JOUR

T1 - Synthesis of 5-amino-3,3-dimethyl-7-phenyl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides

AU - Chioua, Mourad

AU - Samadi, Abdelouahid

AU - Postel, Denis

AU - Balzarini, Jan

AU - Marco-Contelles, José

PY - 2014/9/1

Y1 - 2014/9/1

N2 - The reaction of 4-amino-5,5-dimethyl-5H-1,2-oxathiole 2,2-dioxide (1) with 2-(arylidene)malononitriles 2 in ethanol, at reflux, using piperidine as catalyst, afforded 5-amino-3,3-dimethyl-7-aryl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides (3) in moderate chemical yields.

AB - The reaction of 4-amino-5,5-dimethyl-5H-1,2-oxathiole 2,2-dioxide (1) with 2-(arylidene)malononitriles 2 in ethanol, at reflux, using piperidine as catalyst, afforded 5-amino-3,3-dimethyl-7-aryl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides (3) in moderate chemical yields.

UR - https://www.scopus.com/pages/publications/85028214290

UR - https://www.scopus.com/pages/publications/85028214290#tab=citedBy

U2 - 10.1002/jhet.1678

DO - 10.1002/jhet.1678

M3 - Article

AN - SCOPUS:85028214290

SN - 0022-152X

VL - 51

SP - 1452

EP - 1456

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 5

ER -

Synthesis of 5-amino-3,3-dimethyl-7-phenyl-3H-[1,2]oxathiolo[4,3-b]pyridine-6-carbonitrile 1,1-dioxides

Abstract

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