Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids

Sherzod Turaev; Mukhabbat Yuldasheva

doi:10.1063/5.0089542

Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids

Sherzod Turaev, Mukhabbat Yuldasheva

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Amidoalkylating reagents containing the phthalimide group are used in the synthesis of difficult-to-obtain primary amines and complex heterocyclic compounds. These types of amidoalkylating compounds are a suitable reagent for nucleophilic exchange reactions in acidic environments due to their resistance to acids. Also, the reactions of amidoalkylating reagents-N-β-hydroxyethylphthalimide and N-hydroxymethylphthalimide with aliphatic carbonic acids were carried out in benzene solvent and sulfuric acid catalyst.It was found that the yield of products obtained with N-β-hydroxyethylphthalimide was higher than the yield of reactions with N-hydroxymethylphthalimide. The structure of the obtained compounds was proved by analysis of their IR and NMR H¹ spectra.

Original language	English
Title of host publication	1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021
Editors	Jamoliddin Inotullaevich Razzokov, Mukhabbat Sattorovna Khatamova, Bayramdurdi Sapaev, Elyor Bakhriddinovich Saltov
Publisher	American Institute of Physics Inc.
ISBN (Electronic)	9780735443457
DOIs	https://doi.org/10.1063/5.0089542
Publication status	Published - Jun 16 2022
Externally published	Yes
Event	1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021 - Tashkent, Uzbekistan Duration: Jun 10 2021 → Jun 11 2021

Publication series

Name	AIP Conference Proceedings
Volume	2432
ISSN (Print)	0094-243X
ISSN (Electronic)	1551-7616

Conference

Conference	1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021
Country/Territory	Uzbekistan
City	Tashkent
Period	6/10/21 → 6/11/21

Keywords

N-hydroxymethylphthalimide
N-β-hydroxyethylphthalimide
acetic acid halogen ester
amidoalkylation
haloacetic acid esters

ASJC Scopus subject areas

Physics and Astronomy(all)

Access to Document

10.1063/5.0089542

Cite this

Turaev, S., & Yuldasheva, M. (2022). Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids. In J. I. Razzokov, M. S. Khatamova, B. Sapaev, & E. B. Saltov (Eds.), 1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021 [050033] (AIP Conference Proceedings; Vol. 2432). American Institute of Physics Inc.. https://doi.org/10.1063/5.0089542

Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids. / Turaev, Sherzod; Yuldasheva, Mukhabbat.
1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021. ed. / Jamoliddin Inotullaevich Razzokov; Mukhabbat Sattorovna Khatamova; Bayramdurdi Sapaev; Elyor Bakhriddinovich Saltov. American Institute of Physics Inc., 2022. 050033 (AIP Conference Proceedings; Vol. 2432).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Turaev, S & Yuldasheva, M 2022, Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids. in JI Razzokov, MS Khatamova, B Sapaev & EB Saltov (eds), 1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021., 050033, AIP Conference Proceedings, vol. 2432, American Institute of Physics Inc., 1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021, Tashkent, Uzbekistan, 6/10/21. https://doi.org/10.1063/5.0089542

Turaev S, Yuldasheva M. Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids. In Razzokov JI, Khatamova MS, Sapaev B, Saltov EB, editors, 1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021. American Institute of Physics Inc. 2022. 050033. (AIP Conference Proceedings). doi: 10.1063/5.0089542

Turaev, Sherzod ; Yuldasheva, Mukhabbat. / Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids. 1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021. editor / Jamoliddin Inotullaevich Razzokov ; Mukhabbat Sattorovna Khatamova ; Bayramdurdi Sapaev ; Elyor Bakhriddinovich Saltov. American Institute of Physics Inc., 2022. (AIP Conference Proceedings).

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abstract = "Amidoalkylating reagents containing the phthalimide group are used in the synthesis of difficult-to-obtain primary amines and complex heterocyclic compounds. These types of amidoalkylating compounds are a suitable reagent for nucleophilic exchange reactions in acidic environments due to their resistance to acids. Also, the reactions of amidoalkylating reagents-N-β-hydroxyethylphthalimide and N-hydroxymethylphthalimide with aliphatic carbonic acids were carried out in benzene solvent and sulfuric acid catalyst.It was found that the yield of products obtained with N-β-hydroxyethylphthalimide was higher than the yield of reactions with N-hydroxymethylphthalimide. The structure of the obtained compounds was proved by analysis of their IR and NMR H1 spectra.",

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N2 - Amidoalkylating reagents containing the phthalimide group are used in the synthesis of difficult-to-obtain primary amines and complex heterocyclic compounds. These types of amidoalkylating compounds are a suitable reagent for nucleophilic exchange reactions in acidic environments due to their resistance to acids. Also, the reactions of amidoalkylating reagents-N-β-hydroxyethylphthalimide and N-hydroxymethylphthalimide with aliphatic carbonic acids were carried out in benzene solvent and sulfuric acid catalyst.It was found that the yield of products obtained with N-β-hydroxyethylphthalimide was higher than the yield of reactions with N-hydroxymethylphthalimide. The structure of the obtained compounds was proved by analysis of their IR and NMR H1 spectra.

AB - Amidoalkylating reagents containing the phthalimide group are used in the synthesis of difficult-to-obtain primary amines and complex heterocyclic compounds. These types of amidoalkylating compounds are a suitable reagent for nucleophilic exchange reactions in acidic environments due to their resistance to acids. Also, the reactions of amidoalkylating reagents-N-β-hydroxyethylphthalimide and N-hydroxymethylphthalimide with aliphatic carbonic acids were carried out in benzene solvent and sulfuric acid catalyst.It was found that the yield of products obtained with N-β-hydroxyethylphthalimide was higher than the yield of reactions with N-hydroxymethylphthalimide. The structure of the obtained compounds was proved by analysis of their IR and NMR H1 spectra.

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Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids

Abstract

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