Synthesis of N-β-Hydroxyethylphthalimide and N-Hydroxymethylphthalimide Complex Ethers with Halogen Acetic Acids

Sherzod Turaev, Mukhabbat Yuldasheva

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Amidoalkylating reagents containing the phthalimide group are used in the synthesis of difficult-to-obtain primary amines and complex heterocyclic compounds. These types of amidoalkylating compounds are a suitable reagent for nucleophilic exchange reactions in acidic environments due to their resistance to acids. Also, the reactions of amidoalkylating reagents-N-β-hydroxyethylphthalimide and N-hydroxymethylphthalimide with aliphatic carbonic acids were carried out in benzene solvent and sulfuric acid catalyst.It was found that the yield of products obtained with N-β-hydroxyethylphthalimide was higher than the yield of reactions with N-hydroxymethylphthalimide. The structure of the obtained compounds was proved by analysis of their IR and NMR H1 spectra.

Original languageEnglish
Title of host publication1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021
EditorsJamoliddin Inotullaevich Razzokov, Mukhabbat Sattorovna Khatamova, Bayramdurdi Sapaev, Elyor Bakhriddinovich Saltov
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735443457
DOIs
Publication statusPublished - Jun 16 2022
Externally publishedYes
Event1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021 - Tashkent, Uzbekistan
Duration: Jun 10 2021Jun 11 2021

Publication series

NameAIP Conference Proceedings
Volume2432
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference1st International Conference on Problems and Perspectives of Modern Science, ICPPMS 2021
Country/TerritoryUzbekistan
CityTashkent
Period6/10/216/11/21

Keywords

  • N-hydroxymethylphthalimide
  • N-β-hydroxyethylphthalimide
  • acetic acid halogen ester
  • amidoalkylation
  • haloacetic acid esters

ASJC Scopus subject areas

  • General Physics and Astronomy

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