Synthesis of quinazolines and quinazolinones via palladium-mediated approach

Ibrahim M. Abdou; Shaikha S. Al-Neyadi

doi:10.1515/hc-2014-0181

Synthesis of quinazolines and quinazolinones via palladium-mediated approach

Ibrahim M. Abdou, Shaikha S. Al-Neyadi

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

35 Citations (Scopus)

Abstract

Quinazoline derivatives have drawn attention in the field of heterocyclic chemistry because of their unique skeleton and interesting biological applications. This review summarizes the recent palladium-catalyzed reactions used to construct quinazoline and its related 4(3H)-quinazolinone analogues. The mechanisms of some Pd-catalyzed reactions are also discussed.

Original language	English
Pages (from-to)	115-132
Number of pages	18
Journal	Heterocyclic Communications
Volume	21
Issue number	3
DOIs	https://doi.org/10.1515/hc-2014-0181
Publication status	Published - Jun 1 2015

Keywords

palladium catalysis
quinazolines
quinazolinones
reaction mechanism
synthesis

ASJC Scopus subject areas

Organic Chemistry

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10.1515/hc-2014-0181

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abstract = "Quinazoline derivatives have drawn attention in the field of heterocyclic chemistry because of their unique skeleton and interesting biological applications. This review summarizes the recent palladium-catalyzed reactions used to construct quinazoline and its related 4(3H)-quinazolinone analogues. The mechanisms of some Pd-catalyzed reactions are also discussed.",

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AU - Abdou, Ibrahim M.

AU - Al-Neyadi, Shaikha S.

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Quinazoline derivatives have drawn attention in the field of heterocyclic chemistry because of their unique skeleton and interesting biological applications. This review summarizes the recent palladium-catalyzed reactions used to construct quinazoline and its related 4(3H)-quinazolinone analogues. The mechanisms of some Pd-catalyzed reactions are also discussed.

AB - Quinazoline derivatives have drawn attention in the field of heterocyclic chemistry because of their unique skeleton and interesting biological applications. This review summarizes the recent palladium-catalyzed reactions used to construct quinazoline and its related 4(3H)-quinazolinone analogues. The mechanisms of some Pd-catalyzed reactions are also discussed.

KW - palladium catalysis

KW - quinazolines

KW - quinazolinones

KW - reaction mechanism

KW - synthesis

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M3 - Review article

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JO - Heterocyclic Communications

JF - Heterocyclic Communications

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ER -

Synthesis of quinazolines and quinazolinones via palladium-mediated approach

Abstract

Keywords

ASJC Scopus subject areas

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