TY - JOUR
T1 - Temperament and executive dysfunctions in schizophrenia
AU - Guillem, François
AU - Pampoulova, Tania
AU - Rinaldi, Melissa
AU - Stip, Emmanuel
N1 - Funding Information:
This research was supported by the Canadian Institutes for Health Research (CIHR-MOP-49530) and the Fonds de Recherche en Santé du Québec (FRSQ-Chercheur boursier-3353). The sponsors had no further role in the study design; in the collection, analysis and interpretation of the data; in writing of the report; and in the decision to submit the paper for publication.
PY - 2008/9
Y1 - 2008/9
N2 - Recent studies suggest that both executive dysfunction and personality traits combine with symptoms to affect the social outcome of persons with schizophrenia. This study was designed to investigate how personality traits influence executive function in schizophrenia. Forty-four patients with schizophrenia and twenty-two healthy subjects were assessed for personality using the temperament and character inventory. Different aspects of executive function were assessed using the Auditory Digit Span (forward and backward) and the Wickens' test for proactive interference and release. The results showed that the influences of the various temperament dimensions on specific aspects of executive functions differ between patients and healthy subjects. On some dimensions, schizophrenia appears to reduce the cognitive differences related to temperament. On other dimensions, schizophrenia tends to reverse the cognitive differences related to temperament observed in healthy people. These results suggest that the temperamental profile of schizophrenia patients may well be of important prognostic value in the planning of cognitive enhancement therapy.
AB - Recent studies suggest that both executive dysfunction and personality traits combine with symptoms to affect the social outcome of persons with schizophrenia. This study was designed to investigate how personality traits influence executive function in schizophrenia. Forty-four patients with schizophrenia and twenty-two healthy subjects were assessed for personality using the temperament and character inventory. Different aspects of executive function were assessed using the Auditory Digit Span (forward and backward) and the Wickens' test for proactive interference and release. The results showed that the influences of the various temperament dimensions on specific aspects of executive functions differ between patients and healthy subjects. On some dimensions, schizophrenia appears to reduce the cognitive differences related to temperament. On other dimensions, schizophrenia tends to reverse the cognitive differences related to temperament observed in healthy people. These results suggest that the temperamental profile of schizophrenia patients may well be of important prognostic value in the planning of cognitive enhancement therapy.
KW - Behavioral Activation System
KW - Behavioral Inhibition System
KW - Executive functions
KW - Schizophrenia
KW - Temperament
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U2 - 10.1016/j.schres.2008.06.002
DO - 10.1016/j.schres.2008.06.002
M3 - Article
C2 - 18640010
AN - SCOPUS:50249125862
SN - 0920-9964
VL - 104
SP - 175
EP - 184
JO - Schizophrenia Research
JF - Schizophrenia Research
IS - 1-3
ER -