Temporal characteristics of seizures and epileptiform discharges

C. D. Binnie, J. H.P. Aarts, M. A. Houtkooper, R. Laxminarayan, A. Martins Da Silva, H. Meinardi, N. Nagelkerke, J. Overweg

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)

Abstract

The time relations of epileptic events have been studied in 3 sets of data: (I) counts of individual epileptiform discharges in twelve 48 h EEG recordings, (IIa) seizure calendars of 30 therapy-resistant outpatients participating in a drug trial, (IIb) seizure calendars of 10 mentally subnormal epileptic patients resident in a long-stay unit. The EEG data I were characterized most often by a Poisson distribution of intervals between discharges and the occurrence of marked periodicities, particularly at night. The periods of rhythmic nocturnal events ranged from 13 to 142 min and did not appear to correspond to the REM/non-REM cycle. In the seizure data IIa and b a Poisson distribution of intervals between events was found in half the patients. Periodicities occurred only in group IIa and did not correspond to weekly or monthly cycles. A stochastic process is considered to be the model which best fits these data.

Original languageEnglish
Pages (from-to)498-505
Number of pages8
JournalElectroencephalography and Clinical Neurophysiology
Volume58
Issue number6
DOIs
Publication statusPublished - Dec 1984
Externally publishedYes

ASJC Scopus subject areas

  • General Neuroscience
  • Clinical Neurology

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