Abstract
Objective: To evaluate the effect of risperidone on cognitive functions after both 6 weeks and 6 months of treatment and to determine whether any improvement on neuropsychological function relates to improvement in psychopathology. Method: Patients' psychiatric and extrapyramidal symptoms were assessed while they were receiving classical neuroleptic treatment and adjunctive medications. Patients were then reassessed after changing to a new treatment of risperidone. Results: During treatment with risperidone, schizophrenic patients displayed improved performance mainly on attentional components, specifically, selective attention and alertness. Conclusion: In patients who were given risperidone, there was a positive correlation between improvement in psychopathology and improvement in cognitive tests of explicit memory and alertness.
| Original language | English |
|---|---|
| Pages (from-to) | S35-S40 |
| Journal | Canadian Journal of Psychiatry |
| Volume | 41 |
| Issue number | 8 SUPPL. 2 |
| DOIs | |
| Publication status | Published - Oct 1996 |
| Externally published | Yes |
Keywords
- adverse effects
- attention
- atypical neuroleptics
- cognition
- memory
- risperidone
- schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
