TY - JOUR
T1 - The effects of vitamin B in depression
AU - Mikkelsen, Kathleen
AU - Stojanovska, Lily
AU - Apostolopoulos, Vasso
N1 - Funding Information:
KM was supported by Victoria University Summer Scholarship and 3rd year project study, College of Health and Biomedicine. LS and VA were supported by the Rebecca L Cooper Medical Research Foundation and the Centre for Chronic Disease, College of Health and Biomedicine, Victoria University, Australia. The authors would like to thank Ms. Anne Sced for grammatical editing of the manuscript.
Publisher Copyright:
© 2016 Bentham Science Publishers.
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Vitamins are dietary components which are necessary for life. They play a major role in health and their deficiency may be linked to symptoms of psychiatric disorders. B vitamins are required for proper functioning of the methylation cycle, monoamine oxidase production, DNA synthesis and the repair and maintenance of phospholipids. Vitamin B deficiency could influence memory function, cognitive impairment and dementia. In particular, vitamins B1, B3, B6, B9 and B12 are essential for neuronal function and deficiencies have been linked to depression. We discuss the causes of depression and the neurochemical pathways in depression. In particular, we provide evidence that vitamin B contributes to the complexity of depressive symptoms.
AB - Vitamins are dietary components which are necessary for life. They play a major role in health and their deficiency may be linked to symptoms of psychiatric disorders. B vitamins are required for proper functioning of the methylation cycle, monoamine oxidase production, DNA synthesis and the repair and maintenance of phospholipids. Vitamin B deficiency could influence memory function, cognitive impairment and dementia. In particular, vitamins B1, B3, B6, B9 and B12 are essential for neuronal function and deficiencies have been linked to depression. We discuss the causes of depression and the neurochemical pathways in depression. In particular, we provide evidence that vitamin B contributes to the complexity of depressive symptoms.
KW - Depression
KW - Vitamin B
KW - Vitamin B complex
KW - Vitamin B12
KW - Vitamin B6
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U2 - 10.2174/0929867323666160920110810
DO - 10.2174/0929867323666160920110810
M3 - Article
C2 - 27655070
AN - SCOPUS:85006826119
SN - 0929-8673
VL - 23
SP - 4317
EP - 4337
JO - Current Medicinal Chemistry
JF - Current Medicinal Chemistry
IS - 38
ER -